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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
21.82
Human Site:
S335
Identified Species:
34.29
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S335
T
K
E
G
S
E
F
S
F
S
D
G
E
V
A
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S335
T
K
E
G
S
E
F
S
F
S
D
G
E
V
A
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
S335
T
E
E
R
S
E
F
S
F
S
D
G
E
V
A
Dog
Lupus familis
XP_536291
531
60932
S318
T
E
D
E
S
E
F
S
Y
S
D
E
E
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
T335
T
E
E
D
S
D
F
T
F
S
D
E
E
M
L
Rat
Rattus norvegicus
NP_001009687
551
62702
S335
T
E
E
E
S
D
L
S
L
S
D
E
E
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
P412
L
Q
E
D
I
E
R
P
P
S
G
A
T
P
A
Chicken
Gallus gallus
NP_001006581
551
63395
S331
D
D
H
T
A
E
V
S
E
S
E
E
F
A
E
Frog
Xenopus laevis
NP_001086801
548
62044
G332
D
D
E
N
D
D
D
G
E
T
S
C
K
Q
P
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
S301
C
S
L
D
V
E
I
S
A
S
G
Y
T
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
E330
D
Q
A
D
E
E
D
E
G
E
D
L
E
E
E
Honey Bee
Apis mellifera
XP_623367
426
49113
L219
L
M
N
M
I
V
K
L
G
N
H
G
V
I
H
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
K315
K
M
A
L
D
L
N
K
A
Y
D
E
G
D
F
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
K284
V
A
A
S
G
F
S
K
E
M
E
Q
S
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
V218
S
D
L
M
C
F
I
V
D
L
A
N
S
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
86.6
53.3
N.A.
53.3
46.6
N.A.
26.6
20
6.6
20
N.A.
20
6.6
6.6
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
66.6
N.A.
33.3
33.3
26.6
20
N.A.
26.6
20
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
20
0
7
0
0
0
14
0
7
7
0
7
27
% A
% Cys:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
20
20
7
27
14
20
14
0
7
0
54
0
0
7
0
% D
% Glu:
0
27
47
14
7
54
0
7
20
7
14
34
47
7
27
% E
% Phe:
0
0
0
0
0
14
34
0
27
0
0
0
7
0
7
% F
% Gly:
0
0
0
14
7
0
0
7
14
0
14
27
7
7
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
7
% H
% Ile:
0
0
0
0
14
0
14
0
0
0
0
0
0
7
0
% I
% Lys:
7
14
0
0
0
0
7
14
0
0
0
0
7
7
0
% K
% Leu:
14
0
14
7
0
7
7
7
7
7
0
7
0
7
20
% L
% Met:
0
14
0
14
0
0
0
0
0
7
0
0
0
20
0
% M
% Asn:
0
0
7
7
0
0
7
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
7
% P
% Gln:
0
14
0
0
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
0
7
40
0
7
47
0
60
7
0
14
0
7
% S
% Thr:
40
0
0
7
0
0
0
7
0
7
0
0
14
0
0
% T
% Val:
7
0
0
0
7
7
7
7
0
0
0
0
7
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _