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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIOK2 All Species: 20.3
Human Site: S350 Identified Species: 31.9
UniProt: Q9BVS4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVS4 NP_060813.2 552 63283 S350 E K A E V Y G S E N E S E R N
Chimpanzee Pan troglodytes XP_517843 552 63335 S350 E K A E V Y R S E N E S E Q N
Rhesus Macaque Macaca mulatta XP_001095785 551 63384 S350 E E A E V Y R S E N E S E Q N
Dog Lupus familis XP_536291 531 60932 L333 E K A N V C S L E N Q S D L N
Cat Felis silvestris
Mouse Mus musculus Q9CQS5 547 62472 S350 E K A K V W R S E L E K E A D
Rat Rattus norvegicus NP_001009687 551 62702 S350 E R A K V Q R S E L E N E P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512597 627 71085 S427 R K A E L C R S Q A G S G T D
Chicken Gallus gallus NP_001006581 551 63395 S346 S N L K F F R S N Q E D N V E
Frog Xenopus laevis NP_001086801 548 62044 A347 T E V D G E Q A K S C S S A T
Zebra Danio Brachydanio rerio NP_998719 512 58691 L316 L Q Q D D S L L H P E G P E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651365 538 61413 T345 E E P P T L V T A A S V E I D
Honey Bee Apis mellifera XP_623367 426 49113 I234 G D F N E F N I M I T N S G K
Nematode Worm Caenorhab. elegans NP_493544 529 60467 L330 L A H C E Q E L R N R Q E E D
Sea Urchin Strong. purpuratus XP_784439 491 55586 G299 E V R K I M D G D C E D D E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40160 425 49106 F233 I H C D F N E F N I M I K D K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 81.6 N.A. 82.9 81.6 N.A. 62.5 65.5 67.2 67.3 N.A. 44.3 47.6 41.8 49.4
Protein Similarity: 100 99.6 98.7 88.5 N.A. 91.3 90 N.A. 72 79.1 80 77.9 N.A. 62.6 62.8 60.1 65
P-Site Identity: 100 86.6 80 53.3 N.A. 53.3 53.3 N.A. 33.3 13.3 6.6 6.6 N.A. 13.3 0 13.3 13.3
P-Site Similarity: 100 93.3 93.3 66.6 N.A. 73.3 73.3 N.A. 53.3 26.6 40 26.6 N.A. 33.3 13.3 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 47 0 0 0 0 7 7 14 0 0 0 14 0 % A
% Cys: 0 0 7 7 0 14 0 0 0 7 7 0 0 0 0 % C
% Asp: 0 7 0 20 7 0 7 0 7 0 0 14 14 7 27 % D
% Glu: 54 20 0 27 14 7 14 0 40 0 54 0 47 20 7 % E
% Phe: 0 0 7 0 14 14 0 7 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 7 0 7 7 0 0 7 7 7 7 0 % G
% His: 0 7 7 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 7 0 0 7 0 14 0 7 0 7 0 % I
% Lys: 0 34 0 27 0 0 0 0 7 0 0 7 7 0 14 % K
% Leu: 14 0 7 0 7 7 7 20 0 14 0 0 0 7 0 % L
% Met: 0 0 0 0 0 7 0 0 7 0 7 0 0 0 0 % M
% Asn: 0 7 0 14 0 7 7 0 14 34 0 14 7 0 34 % N
% Pro: 0 0 7 7 0 0 0 0 0 7 0 0 7 7 0 % P
% Gln: 0 7 7 0 0 14 7 0 7 7 7 7 0 14 0 % Q
% Arg: 7 7 7 0 0 0 40 0 7 0 7 0 0 7 0 % R
% Ser: 7 0 0 0 0 7 7 47 0 7 7 40 14 0 7 % S
% Thr: 7 0 0 0 7 0 0 7 0 0 7 0 0 7 14 % T
% Val: 0 7 7 0 40 0 7 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _