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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
12.73
Human Site:
S390
Identified Species:
20
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S390
E
E
S
A
D
A
R
S
F
E
M
T
E
F
N
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S390
E
E
S
A
D
A
R
S
F
E
M
T
E
F
D
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
C390
K
E
S
A
D
A
R
C
F
E
M
T
E
F
N
Dog
Lupus familis
XP_536291
531
60932
L373
E
S
A
H
N
F
E
L
P
E
L
S
Q
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
S390
E
E
S
A
H
V
S
S
F
E
V
T
A
L
S
Rat
Rattus norvegicus
NP_001009687
551
62702
S390
E
E
S
A
D
V
S
S
F
E
V
T
K
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
G467
G
D
G
A
R
D
V
G
A
A
S
G
T
R
Q
Chicken
Gallus gallus
NP_001006581
551
63395
K386
E
T
S
E
N
L
Q
K
L
S
L
T
E
S
S
Frog
Xenopus laevis
NP_001086801
548
62044
F387
Q
G
I
D
M
A
E
F
T
K
A
V
A
E
L
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
M356
M
E
E
F
K
H
A
M
L
E
L
Q
G
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
T385
R
R
Y
I
E
S
C
T
Q
Y
L
G
N
L
S
Honey Bee
Apis mellifera
XP_623367
426
49113
K274
N
C
V
R
D
F
F
K
R
R
F
G
Y
E
S
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
A370
K
D
H
E
E
L
Q
A
Q
E
N
T
V
K
Q
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
E339
S
E
D
K
N
S
E
E
V
Q
S
I
R
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
V273
D
Y
Y
F
Q
R
D
V
D
C
I
R
R
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
93.3
86.6
13.3
N.A.
53.3
60
N.A.
6.6
26.6
6.6
13.3
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
100
93.3
46.6
N.A.
66.6
80
N.A.
13.3
53.3
20
20
N.A.
33.3
13.3
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
40
0
27
7
7
7
7
7
0
14
7
0
% A
% Cys:
0
7
0
0
0
0
7
7
0
7
0
0
0
0
0
% C
% Asp:
7
14
7
7
34
7
7
0
7
0
0
0
0
0
14
% D
% Glu:
40
47
7
14
14
0
20
7
0
54
0
0
27
20
0
% E
% Phe:
0
0
0
14
0
14
7
7
34
0
7
0
0
27
7
% F
% Gly:
7
7
7
0
0
0
0
7
0
0
0
20
7
0
0
% G
% His:
0
0
7
7
7
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
7
7
0
0
0
0
0
0
7
7
0
0
0
% I
% Lys:
14
0
0
7
7
0
0
14
0
7
0
0
7
7
7
% K
% Leu:
0
0
0
0
0
14
0
7
14
0
27
0
0
27
14
% L
% Met:
7
0
0
0
7
0
0
7
0
0
20
0
0
0
0
% M
% Asn:
7
0
0
0
20
0
0
0
0
0
7
0
7
0
14
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
7
0
14
0
14
7
0
7
7
0
14
% Q
% Arg:
7
7
0
7
7
7
20
0
7
7
0
7
14
7
0
% R
% Ser:
7
7
40
0
0
14
14
27
0
7
14
7
0
7
27
% S
% Thr:
0
7
0
0
0
0
0
7
7
0
0
47
7
0
0
% T
% Val:
0
0
7
0
0
14
7
7
7
0
14
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
14
0
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _