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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIOK2 All Species: 36.36
Human Site: S489 Identified Species: 57.14
UniProt: Q9BVS4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVS4 NP_060813.2 552 63283 S489 L S I T S S G S A V S C S T I
Chimpanzee Pan troglodytes XP_517843 552 63335 S489 L S I T S S G S A V S C S T I
Rhesus Macaque Macaca mulatta XP_001095785 551 63384 S488 L S I T S S G S V V S C S T I
Dog Lupus familis XP_536291 531 60932 S468 L S V T S V G S V L S C S T I
Cat Felis silvestris
Mouse Mus musculus Q9CQS5 547 62472 S484 L S V T S A G S A L S C S T I
Rat Rattus norvegicus NP_001009687 551 62702 S488 L S V T S T G S V L S C S T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512597 627 71085 S565 Q S V T S M G S V G G C S T I
Chicken Gallus gallus NP_001006581 551 63395 S489 T R T T S V S S L G S C S T I
Frog Xenopus laevis NP_001086801 548 62044 T486 T S V T S I G T V G S C S T I
Zebra Danio Brachydanio rerio NP_998719 512 58691 S450 T S E M S M A S V A S C S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651365 538 61413 R476 L N D A R S Q R S Y S T T T S
Honey Bee Apis mellifera XP_623367 426 49113 S364 S D S K S I Y S T T T A A T I
Nematode Worm Caenorhab. elegans NP_493544 529 60467 K464 V A K V V K K K R V P S G A R
Sea Urchin Strong. purpuratus XP_784439 491 55586 S429 R N S D S I S S Y T S T S S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40160 425 49106 A363 D D M S N D E A E E E N G E G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 81.6 N.A. 82.9 81.6 N.A. 62.5 65.5 67.2 67.3 N.A. 44.3 47.6 41.8 49.4
Protein Similarity: 100 99.6 98.7 88.5 N.A. 91.3 90 N.A. 72 79.1 80 77.9 N.A. 62.6 62.8 60.1 65
P-Site Identity: 100 100 93.3 73.3 N.A. 80 73.3 N.A. 60 53.3 60 53.3 N.A. 26.6 26.6 6.6 26.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 100 93.3 N.A. 66.6 53.3 73.3 53.3 N.A. 46.6 40 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 7 7 7 20 7 0 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 % C
% Asp: 7 14 7 7 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 7 0 7 7 7 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 54 0 0 20 7 0 14 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 20 0 0 0 0 0 0 0 0 74 % I
% Lys: 0 0 7 7 0 7 7 7 0 0 0 0 0 0 0 % K
% Leu: 47 0 0 0 0 0 0 0 7 20 0 0 0 0 0 % L
% Met: 0 0 7 7 0 14 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 0 0 7 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 7 7 0 0 7 0 0 7 7 0 0 0 0 0 7 % R
% Ser: 7 60 14 7 80 27 14 74 7 0 74 7 74 7 7 % S
% Thr: 20 0 7 60 0 7 0 7 7 14 7 14 7 80 7 % T
% Val: 7 0 34 7 7 14 0 0 40 27 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 7 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _