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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
36.97
Human Site:
S492
Identified Species:
58.1
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S492
T
S
S
G
S
A
V
S
C
S
T
I
P
P
E
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S492
T
S
S
G
S
A
V
S
C
S
T
I
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
S491
T
S
S
G
S
V
V
S
C
S
T
I
P
P
E
Dog
Lupus familis
XP_536291
531
60932
S471
T
S
V
G
S
V
L
S
C
S
T
I
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
S487
T
S
A
G
S
A
L
S
C
S
T
I
P
P
E
Rat
Rattus norvegicus
NP_001009687
551
62702
S491
T
S
T
G
S
V
L
S
C
S
T
I
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
G568
T
S
M
G
S
V
G
G
C
S
T
I
P
P
E
Chicken
Gallus gallus
NP_001006581
551
63395
S492
T
S
V
S
S
L
G
S
C
S
T
I
P
P
E
Frog
Xenopus laevis
NP_001086801
548
62044
S489
T
S
I
G
T
V
G
S
C
S
T
I
P
P
E
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
S453
M
S
M
A
S
V
A
S
C
S
T
I
P
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
S479
A
R
S
Q
R
S
Y
S
T
T
T
S
T
I
A
Honey Bee
Apis mellifera
XP_623367
426
49113
T367
K
S
I
Y
S
T
T
T
A
A
T
I
A
P
E
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
P467
V
V
K
K
K
R
V
P
S
G
A
R
S
V
A
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
S432
D
S
I
S
S
Y
T
S
T
S
S
T
M
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
E366
S
N
D
E
A
E
E
E
N
G
E
G
D
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
73.3
73.3
73.3
66.6
N.A.
20
40
6.6
26.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
100
93.3
N.A.
73.3
73.3
80
66.6
N.A.
33.3
53.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
20
7
0
7
7
7
0
7
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
7
0
7
7
7
0
0
7
0
0
0
74
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
54
0
0
20
7
0
14
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
0
74
0
7
0
% I
% Lys:
7
0
7
7
7
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
7
20
0
0
0
0
0
0
0
0
% L
% Met:
7
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
67
74
7
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
7
80
27
14
74
7
0
74
7
74
7
7
7
0
7
% S
% Thr:
60
0
7
0
7
7
14
7
14
7
80
7
7
0
0
% T
% Val:
7
7
14
0
0
40
27
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
7
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _