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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
15.45
Human Site:
T423
Identified Species:
24.29
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
T423
F
S
E
E
K
N
R
T
E
N
Y
N
R
Q
D
Chimpanzee
Pan troglodytes
XP_517843
552
63335
T423
F
S
E
E
K
N
R
T
E
N
Y
N
R
Q
D
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
T423
F
S
E
E
K
S
R
T
E
N
Y
N
G
Q
D
Dog
Lupus familis
XP_536291
531
60932
T403
Y
S
E
E
K
N
K
T
K
N
D
T
R
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
R422
E
F
S
E
E
S
R
R
T
E
N
D
G
Q
P
Rat
Rattus norvegicus
NP_001009687
551
62702
T423
V
S
E
E
S
T
R
T
E
D
D
P
R
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
P500
F
P
E
G
E
N
E
P
E
D
A
A
E
R
D
Chicken
Gallus gallus
NP_001006581
551
63395
P420
V
S
Y
V
T
L
F
P
E
H
E
R
M
L
E
Frog
Xenopus laevis
NP_001086801
548
62044
D419
L
E
D
E
R
L
I
D
A
N
S
E
R
E
D
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
V386
G
A
R
C
E
Q
D
V
P
S
E
D
L
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
P415
I
S
L
P
A
E
T
P
D
V
I
P
F
E
A
Honey Bee
Apis mellifera
XP_623367
426
49113
G304
D
V
E
I
K
A
S
G
L
T
K
Q
M
E
K
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
V402
A
T
N
Q
L
E
A
V
D
L
D
A
L
K
S
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
D369
E
H
C
I
M
V
M
D
G
N
E
Q
E
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
G303
D
T
E
G
F
G
D
G
Y
K
Y
A
Y
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
86.6
66.6
N.A.
20
53.3
N.A.
33.3
13.3
26.6
6.6
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
40
60
N.A.
53.3
26.6
46.6
33.3
N.A.
20
20
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
7
7
0
7
0
7
20
0
0
7
% A
% Cys:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
7
0
0
0
14
14
14
14
20
14
0
0
54
% D
% Glu:
14
7
54
47
20
14
7
0
40
7
20
7
14
20
7
% E
% Phe:
27
7
0
0
7
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
14
0
7
0
14
7
0
0
0
14
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
7
0
0
14
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
34
0
7
0
7
7
7
0
0
7
7
% K
% Leu:
7
0
7
0
7
14
0
0
7
7
0
0
14
7
0
% L
% Met:
0
0
0
0
7
0
7
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
7
0
0
27
0
0
0
40
7
20
0
0
0
% N
% Pro:
0
7
0
7
0
0
0
20
7
0
0
14
0
7
7
% P
% Gln:
0
0
0
7
0
7
0
0
0
0
0
14
0
47
0
% Q
% Arg:
0
0
7
0
7
0
34
7
0
0
0
7
34
7
0
% R
% Ser:
0
47
7
0
7
14
7
0
0
7
7
0
0
0
14
% S
% Thr:
0
14
0
0
7
7
7
34
7
7
0
7
0
0
7
% T
% Val:
14
7
0
7
0
7
0
14
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
7
0
27
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _