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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIPIN
All Species:
11.82
Human Site:
T224
Identified Species:
23.64
UniProt:
Q9BVW5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVW5
NP_060328.2
301
34496
T224
K
L
L
S
N
S
Q
T
L
G
N
D
M
L
M
Chimpanzee
Pan troglodytes
XP_510492
302
34630
T225
K
L
L
S
N
S
Q
T
L
G
N
D
M
L
M
Rhesus Macaque
Macaca mulatta
XP_001110143
307
35186
S224
K
L
L
S
N
S
Q
S
L
E
N
D
M
L
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91WA1
278
31479
Q205
Q
R
I
E
R
N
K
Q
L
A
L
E
R
R
Q
Rat
Rattus norvegicus
Q4QR88
276
31119
D180
A
F
V
T
S
S
S
D
S
K
R
F
A
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511348
284
32365
E212
R
N
R
R
L
A
L
E
R
R
Q
A
K
L
V
Chicken
Gallus gallus
Q5F416
283
31809
T197
E
L
D
S
L
P
G
T
T
L
T
E
E
Q
Q
Frog
Xenopus laevis
Q0IHI4
360
40318
N242
Q
A
T
Q
S
D
P
N
E
I
P
D
D
A
F
Zebra Danio
Brachydanio rerio
Q6DBR4
294
33162
Q222
R
R
L
A
K
Q
K
Q
L
E
S
T
P
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INX3
307
34103
T224
R
G
N
A
V
M
S
T
P
Y
S
G
V
N
A
Honey Bee
Apis mellifera
XP_001121761
242
28763
I166
D
L
L
I
A
E
Q
I
E
K
Q
K
Q
V
M
Nematode Worm
Caenorhab. elegans
Q9TXI0
233
27059
D161
D
D
G
A
S
D
N
D
D
D
L
F
K
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
92.5
N.A.
N.A.
71
68.1
N.A.
56.1
51.8
43.3
46.1
N.A.
21.5
24.2
21.5
N.A.
Protein Similarity:
100
98
94.4
N.A.
N.A.
79.4
77.4
N.A.
70
66.4
56.6
62.7
N.A.
41.3
47.5
41.5
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
6.6
N.A.
6.6
20
6.6
13.3
N.A.
6.6
26.6
0
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
40
26.6
N.A.
26.6
33.3
20
46.6
N.A.
33.3
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
25
9
9
0
0
0
9
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
0
0
17
0
17
9
9
0
34
9
9
0
% D
% Glu:
9
0
0
9
0
9
0
9
17
17
0
17
9
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
17
0
0
9
% F
% Gly:
0
9
9
0
0
0
9
0
0
17
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
9
0
9
0
0
0
9
0
% I
% Lys:
25
0
0
0
9
0
17
0
0
17
0
9
17
0
0
% K
% Leu:
0
42
42
0
17
0
9
0
42
9
17
0
0
34
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
25
0
34
% M
% Asn:
0
9
9
0
25
9
9
9
0
0
25
0
0
9
0
% N
% Pro:
0
0
0
0
0
9
9
0
9
0
9
0
9
0
0
% P
% Gln:
17
0
0
9
0
9
34
17
0
0
17
0
9
9
17
% Q
% Arg:
25
17
9
9
9
0
0
0
9
9
9
0
9
9
0
% R
% Ser:
0
0
0
34
25
34
17
9
9
0
17
0
0
9
9
% S
% Thr:
0
0
9
9
0
0
0
34
9
0
9
9
0
0
0
% T
% Val:
0
0
9
0
9
0
0
0
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _