Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIFC1 All Species: 13.03
Human Site: S246 Identified Species: 20.48
UniProt: Q9BW19 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW19 NP_002254.2 673 73748 S246 E E R R G L M S Q L E E K E R
Chimpanzee Pan troglodytes XP_518406 724 78505 E338 A K V Q A Q A E Q G Q Q E L K
Rhesus Macaque Macaca mulatta XP_001109683 589 64547 L188 S R A E V A S L W Q E T A A Q
Dog Lupus familis XP_849869 798 86433 A332 E E R R G L A A R L E E Q E R
Cat Felis silvestris
Mouse Mus musculus Q9QWT9 674 74134 T247 E E R S T L S T Q L E E Q E R
Rat Rattus norvegicus Q5XI63 693 76123 T266 E E R S T L S T Q L E E R E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001075167 647 71757 A208 E A D R E L S A R L E A A E A
Frog Xenopus laevis P79955 643 71930 K230 G A N A I L T K Q L L D K E V
Zebra Danio Brachydanio rerio NP_001038419 618 69285 S209 G L R D H L E S E L R N I Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 E287 S E L Q A I H E K V K T E H A
Honey Bee Apis mellifera XP_001122238 580 65580 T189 N L K K Y L E T N L E A E R K
Nematode Worm Caenorhab. elegans P45962 598 67305 L191 E K D E L K R L A L D T K D A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316967 712 80158 S276 T L V N E V A S L R A E L Q Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46864 745 84341 D323 K E I E E L Q D Q L V A S E R
Baker's Yeast Sacchar. cerevisiae P17119 729 83985 P294 E I E N T L K P E L A E K K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 85.7 73 N.A. 79.8 77.1 N.A. N.A. 49.3 44.5 43 N.A. 28.2 35.3 29.5 N.A.
Protein Similarity: 100 80.2 86 76.9 N.A. 87.2 84.8 N.A. N.A. 63.1 60.3 58.5 N.A. 44.5 53 47.9 N.A.
P-Site Identity: 100 6.6 6.6 73.3 N.A. 66.6 66.6 N.A. N.A. 40 33.3 26.6 N.A. 6.6 20 20 N.A.
P-Site Similarity: 100 46.6 13.3 93.3 N.A. 80 80 N.A. N.A. 53.3 40 40 N.A. 46.6 53.3 40 N.A.
Percent
Protein Identity: 33.1 N.A. N.A. 32.4 31.6 N.A.
Protein Similarity: 49.5 N.A. N.A. 48.9 49.1 N.A.
P-Site Identity: 13.3 N.A. N.A. 40 33.3 N.A.
P-Site Similarity: 33.3 N.A. N.A. 46.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 7 14 7 20 14 7 0 14 20 14 7 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 14 7 0 0 0 7 0 0 7 7 0 7 0 % D
% Glu: 47 40 7 20 20 0 14 14 14 0 47 40 20 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 14 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 7 0 7 7 0 0 0 0 0 0 7 0 0 % I
% Lys: 7 14 7 7 0 7 7 7 7 0 7 0 27 7 20 % K
% Leu: 0 20 7 0 7 67 0 14 7 74 7 0 7 7 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 14 0 0 0 0 7 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 14 0 7 7 0 40 7 7 7 14 14 14 % Q
% Arg: 0 7 34 20 0 0 7 0 14 7 7 0 7 7 34 % R
% Ser: 14 0 0 14 0 0 27 20 0 0 0 0 7 0 0 % S
% Thr: 7 0 0 0 20 0 7 20 0 0 0 20 0 0 7 % T
% Val: 0 0 14 0 7 7 0 0 0 7 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _