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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIFC1 All Species: 15.15
Human Site: S265 Identified Species: 23.81
UniProt: Q9BW19 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW19 NP_002254.2 673 73748 S265 S E A A L S S S Q A E V A S L
Chimpanzee Pan troglodytes XP_518406 724 78505 R357 C V L E L E E R L S T Q E G L
Rhesus Macaque Macaca mulatta XP_001109683 589 64547 H207 A E R E E R L H G L E M E R R
Dog Lupus familis XP_849869 798 86433 S351 S E A A L S G S Q A E V A S L
Cat Felis silvestris
Mouse Mus musculus Q9QWT9 674 74134 S266 T E A A L S S S Q E E V V C L
Rat Rattus norvegicus Q5XI63 693 76123 S285 S E A A L S S S R A E V L C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001075167 647 71757 S227 T K A V L A Q S D S E V A E L
Frog Xenopus laevis P79955 643 71930 L249 V S G E N T S L K H T V N E Q
Zebra Danio Brachydanio rerio NP_001038419 618 69285 C228 Q T S A L G R C Q D S L K E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 R306 E V V H L R Q R T E E L L R C
Honey Bee Apis mellifera XP_001122238 580 65580 L208 L T T D K N D L Q S L V H T M
Nematode Worm Caenorhab. elegans P45962 598 67305 L210 M A E M R M M L T S K T T D F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316967 712 80158 V295 R D S L L L Q V Q T L T A E V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46864 745 84341 K342 A D L S T F E K M N E F E E Q
Baker's Yeast Sacchar. cerevisiae P17119 729 83985 I313 K R N A Y E A I K V K V K E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 85.7 73 N.A. 79.8 77.1 N.A. N.A. 49.3 44.5 43 N.A. 28.2 35.3 29.5 N.A.
Protein Similarity: 100 80.2 86 76.9 N.A. 87.2 84.8 N.A. N.A. 63.1 60.3 58.5 N.A. 44.5 53 47.9 N.A.
P-Site Identity: 100 13.3 13.3 93.3 N.A. 73.3 80 N.A. N.A. 46.6 13.3 20 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 20 26.6 93.3 N.A. 80 86.6 N.A. N.A. 73.3 26.6 33.3 N.A. 20 40 13.3 N.A.
Percent
Protein Identity: 33.1 N.A. N.A. 32.4 31.6 N.A.
Protein Similarity: 49.5 N.A. N.A. 48.9 49.1 N.A.
P-Site Identity: 20 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 34 40 0 7 7 0 0 20 0 0 27 0 0 % A
% Cys: 7 0 0 0 0 0 0 7 0 0 0 0 0 14 7 % C
% Asp: 0 14 0 7 0 0 7 0 7 7 0 0 0 7 0 % D
% Glu: 7 34 7 20 7 14 14 0 0 14 54 0 20 40 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 7 % F
% Gly: 0 0 7 0 0 7 7 0 7 0 0 0 0 7 0 % G
% His: 0 0 0 7 0 0 0 7 0 7 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 7 0 0 7 0 0 7 14 0 14 0 14 0 7 % K
% Leu: 7 0 14 7 60 7 7 20 7 7 14 14 14 0 40 % L
% Met: 7 0 0 7 0 7 7 0 7 0 0 7 0 0 7 % M
% Asn: 0 0 7 0 7 7 0 0 0 7 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 20 0 40 0 0 7 0 0 14 % Q
% Arg: 7 7 7 0 7 14 7 14 7 0 0 0 0 14 7 % R
% Ser: 20 7 14 7 0 27 27 34 0 27 7 0 0 14 7 % S
% Thr: 14 14 7 0 7 7 0 0 14 7 14 14 7 7 0 % T
% Val: 7 14 7 7 0 0 0 7 0 7 0 54 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _