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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIFC1
All Species:
20.3
Human Site:
S494
Identified Species:
31.9
UniProt:
Q9BW19
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BW19
NP_002254.2
673
73748
S494
I
R
R
A
G
P
G
S
E
E
L
T
V
T
N
Chimpanzee
Pan troglodytes
XP_518406
724
78505
Q549
V
C
I
F
A
Y
G
Q
T
G
S
G
K
T
F
Rhesus Macaque
Macaca mulatta
XP_001109683
589
64547
S410
I
R
R
A
G
P
G
S
E
E
L
T
V
T
N
Dog
Lupus familis
XP_849869
798
86433
S580
I
R
R
A
G
P
G
S
E
E
L
T
V
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWT9
674
74134
S495
I
R
R
A
S
P
G
S
E
E
L
T
V
T
N
Rat
Rattus norvegicus
Q5XI63
693
76123
S514
I
R
R
A
G
P
G
S
E
E
L
T
V
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001075167
647
71757
E473
R
R
V
S
S
A
S
E
E
L
H
V
P
N
L
Frog
Xenopus laevis
P79955
643
71930
N468
I
R
K
V
N
S
A
N
M
L
L
Y
V
T
N
Zebra Danio
Brachydanio rerio
NP_001038419
618
69285
E445
I
R
K
V
S
N
N
E
I
T
V
T
N
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20480
700
77455
I512
A
K
N
N
K
N
D
I
Y
V
S
N
I
T
E
Honey Bee
Apis mellifera
XP_001122238
580
65580
Y405
D
S
K
G
H
D
L
Y
V
S
N
L
K
I
E
Nematode Worm
Caenorhab. elegans
P45962
598
67305
I405
T
E
E
G
R
S
S
I
P
G
L
E
E
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316967
712
80158
N526
Y
A
I
K
H
D
A
N
G
N
T
L
V
S
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46864
745
84341
H556
P
Q
K
Y
A
I
K
H
D
A
S
G
N
T
H
Baker's Yeast
Sacchar. cerevisiae
P17119
729
83985
T555
E
I
R
H
D
Q
E
T
K
T
T
T
I
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
85.7
73
N.A.
79.8
77.1
N.A.
N.A.
49.3
44.5
43
N.A.
28.2
35.3
29.5
N.A.
Protein Similarity:
100
80.2
86
76.9
N.A.
87.2
84.8
N.A.
N.A.
63.1
60.3
58.5
N.A.
44.5
53
47.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
N.A.
13.3
40
20
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
100
N.A.
N.A.
20
53.3
33.3
N.A.
20
6.6
13.3
N.A.
Percent
Protein Identity:
33.1
N.A.
N.A.
32.4
31.6
N.A.
Protein Similarity:
49.5
N.A.
N.A.
48.9
49.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
34
14
7
14
0
0
7
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
14
7
0
7
0
0
0
0
0
7
% D
% Glu:
7
7
7
0
0
0
7
14
40
34
0
7
7
0
14
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
14
27
0
40
0
7
14
0
14
0
0
0
% G
% His:
0
0
0
7
14
0
0
7
0
0
7
0
0
0
7
% H
% Ile:
47
7
14
0
0
7
0
14
7
0
0
0
14
7
0
% I
% Lys:
0
7
27
7
7
0
7
0
7
0
0
0
14
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
14
47
14
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
14
7
14
0
7
7
7
14
7
47
% N
% Pro:
7
0
0
0
0
34
0
0
7
0
0
0
7
0
0
% P
% Gln:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
54
40
0
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
7
20
14
14
34
0
7
20
0
0
7
7
% S
% Thr:
7
0
0
0
0
0
0
7
7
14
14
47
0
67
7
% T
% Val:
7
0
7
14
0
0
0
0
7
7
7
7
47
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
7
0
7
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _