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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIFC1 All Species: 16.06
Human Site: T346 Identified Species: 25.24
UniProt: Q9BW19 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW19 NP_002254.2 673 73748 T346 G G P S D P P T R L S L S R S
Chimpanzee Pan troglodytes XP_518406 724 78505 R411 Q A E V A S L R Q E T V A Q A
Rhesus Macaque Macaca mulatta XP_001109683 589 64547 T262 G V P S D P P T R L S L S R S
Dog Lupus familis XP_849869 798 86433 T432 G G P A D L P T R L S V S R C
Cat Felis silvestris
Mouse Mus musculus Q9QWT9 674 74134 T347 A G P S D P P T G L S L S R S
Rat Rattus norvegicus Q5XI63 693 76123 T366 A G P S D P P T R L C L S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001075167 647 71757 D327 H L H F P P Q D N K T L V L L
Frog Xenopus laevis P79955 643 71930 D322 H I S F P S N D G K A I V L S
Zebra Danio Brachydanio rerio NP_001038419 618 69285 D300 H I Q L P P H D N K A L T L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 W370 E N R M C C T W T Y H D E S T
Honey Bee Apis mellifera XP_001122238 580 65580 G265 D E C T I E V G K F D G S D A
Nematode Worm Caenorhab. elegans P45962 598 67305 K264 A S E T D N Q K P V V V I D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316967 712 80158 K376 D S P G A D G K V V S Y P T T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46864 745 84341 K408 E N S S E E A K T I S Y P T S
Baker's Yeast Sacchar. cerevisiae P17119 729 83985 V410 S D T S L I N V N E F D D N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 85.7 73 N.A. 79.8 77.1 N.A. N.A. 49.3 44.5 43 N.A. 28.2 35.3 29.5 N.A.
Protein Similarity: 100 80.2 86 76.9 N.A. 87.2 84.8 N.A. N.A. 63.1 60.3 58.5 N.A. 44.5 53 47.9 N.A.
P-Site Identity: 100 0 93.3 73.3 N.A. 86.6 86.6 N.A. N.A. 13.3 6.6 13.3 N.A. 0 6.6 6.6 N.A.
P-Site Similarity: 100 40 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 20 20 33.3 N.A. 6.6 26.6 26.6 N.A.
Percent
Protein Identity: 33.1 N.A. N.A. 32.4 31.6 N.A.
Protein Similarity: 49.5 N.A. N.A. 48.9 49.1 N.A.
P-Site Identity: 13.3 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 0 7 14 0 7 0 0 0 14 0 7 0 20 % A
% Cys: 0 0 7 0 7 7 0 0 0 0 7 0 0 0 7 % C
% Asp: 14 7 0 0 40 7 0 20 0 0 7 14 7 14 0 % D
% Glu: 14 7 14 0 7 14 0 0 0 14 0 0 7 0 7 % E
% Phe: 0 0 0 14 0 0 0 0 0 7 7 0 0 0 0 % F
% Gly: 20 27 0 7 0 0 7 7 14 0 0 7 0 0 0 % G
% His: 20 0 7 0 0 0 7 0 0 0 7 0 0 0 0 % H
% Ile: 0 14 0 0 7 7 0 0 0 7 0 7 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 20 7 20 0 0 0 0 0 % K
% Leu: 0 7 0 7 7 7 7 0 0 34 0 40 0 20 7 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 14 0 0 0 7 14 0 20 0 0 0 0 7 0 % N
% Pro: 0 0 40 0 20 40 34 0 7 0 0 0 14 0 0 % P
% Gln: 7 0 7 0 0 0 14 0 7 0 0 0 0 7 0 % Q
% Arg: 0 0 7 0 0 0 0 7 27 0 0 0 0 34 0 % R
% Ser: 7 14 14 40 0 14 0 0 0 0 40 0 40 7 47 % S
% Thr: 0 0 7 14 0 0 7 34 14 0 14 0 7 14 14 % T
% Val: 0 7 0 7 0 0 7 7 7 14 7 20 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _