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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIFC1 All Species: 28.79
Human Site: T475 Identified Species: 45.24
UniProt: Q9BW19 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW19 NP_002254.2 673 73748 T475 T V R D L L A T G T R K G Q G
Chimpanzee Pan troglodytes XP_518406 724 78505 L532 V F E E I A M L V Q S A L D G
Rhesus Macaque Macaca mulatta XP_001109683 589 64547 T391 T V R D L L A T G T R K G Q G
Dog Lupus familis XP_849869 798 86433 T561 T V R D L L A T G P R K G Q G
Cat Felis silvestris
Mouse Mus musculus Q9QWT9 674 74134 T476 T V R D L L A T G P R K G Q G
Rat Rattus norvegicus Q5XI63 693 76123 T495 T V R D L L A T G T R K G Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001075167 647 71757 A456 S L R D L L G A R P E C G E L
Frog Xenopus laevis P79955 643 71930 N451 T I R D L L I N R P D K K L E
Zebra Danio Brachydanio rerio NP_001038419 618 69285 K427 T L R D L L Y K G K P N K R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 N495 V L Y D L L S N E Q K D M E I
Honey Bee Apis mellifera XP_001122238 580 65580 S387 H I V D L L D S Q S K I H E I
Nematode Worm Caenorhab. elegans P45962 598 67305 T388 K I R D L L N T S N T N L A I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316967 712 80158 T504 T I R D L L S T K D P S R T E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46864 745 84341 T536 T I R D L L S T N K E A V R A
Baker's Yeast Sacchar. cerevisiae P17119 729 83985 S533 N I V D L L R S D N N N K E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 85.7 73 N.A. 79.8 77.1 N.A. N.A. 49.3 44.5 43 N.A. 28.2 35.3 29.5 N.A.
Protein Similarity: 100 80.2 86 76.9 N.A. 87.2 84.8 N.A. N.A. 63.1 60.3 58.5 N.A. 44.5 53 47.9 N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 100 N.A. N.A. 33.3 40 40 N.A. 20 20 33.3 N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 93.3 100 N.A. N.A. 53.3 46.6 53.3 N.A. 46.6 53.3 40 N.A.
Percent
Protein Identity: 33.1 N.A. N.A. 32.4 31.6 N.A.
Protein Similarity: 49.5 N.A. N.A. 48.9 49.1 N.A.
P-Site Identity: 40 N.A. N.A. 40 20 N.A.
P-Site Similarity: 53.3 N.A. N.A. 60 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 34 7 0 0 0 14 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 94 0 0 7 0 7 7 7 7 0 7 7 % D
% Glu: 0 0 7 7 0 0 0 0 7 0 14 0 0 27 14 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 40 0 0 0 40 0 40 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 40 0 0 7 0 7 0 0 0 0 7 0 0 20 % I
% Lys: 7 0 0 0 0 0 0 7 7 14 14 40 20 0 0 % K
% Leu: 0 20 0 0 94 94 0 7 0 0 0 0 14 7 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 0 0 0 7 14 7 14 7 20 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 27 14 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 7 14 0 0 0 34 0 % Q
% Arg: 0 0 74 0 0 0 7 0 14 0 34 0 7 14 0 % R
% Ser: 7 0 0 0 0 0 20 14 7 7 7 7 0 0 0 % S
% Thr: 60 0 0 0 0 0 0 54 0 20 7 0 0 7 0 % T
% Val: 14 34 14 0 0 0 0 0 7 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _