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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIFC1 All Species: 7.88
Human Site: T74 Identified Species: 12.38
UniProt: Q9BW19 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW19 NP_002254.2 673 73748 T74 P R V P S L T T V P Q T Q G Q
Chimpanzee Pan troglodytes XP_518406 724 78505 T211 P R V P S L T T V P Q T Q G Q
Rhesus Macaque Macaca mulatta XP_001109683 589 64547 A64 G Q L C D L N A E L K R C R E
Dog Lupus familis XP_849869 798 86433 A161 S R A P A L T A R T Q T Q N Q
Cat Felis silvestris
Mouse Mus musculus Q9QWT9 674 74134 T76 P R G P L L S T V S Q T Q G H
Rat Rattus norvegicus Q5XI63 693 76123 G95 V D T S R P R G P P L S A V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001075167 647 71757 A75 L R A L S V P A A P G P G P P
Frog Xenopus laevis P79955 643 71930 R82 R Q S L A V M R P K N S G P G
Zebra Danio Brachydanio rerio NP_001038419 618 69285 P66 A V K A P V K P L R P T G A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20480 700 77455 G105 C D I N E L R G N K R T A A A
Honey Bee Apis mellifera XP_001122238 580 65580 K65 A K C R N E N K P P A K Q I L
Nematode Worm Caenorhab. elegans P45962 598 67305 R67 M E D F I Q G R A T S Y T N R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316967 712 80158 V128 E E L N L I I V E L R K S L A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46864 745 84341 D120 E E L N M V I D E L R K N F A
Baker's Yeast Sacchar. cerevisiae P17119 729 83985 F113 N R T Q A I L F E K K A T L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 85.7 73 N.A. 79.8 77.1 N.A. N.A. 49.3 44.5 43 N.A. 28.2 35.3 29.5 N.A.
Protein Similarity: 100 80.2 86 76.9 N.A. 87.2 84.8 N.A. N.A. 63.1 60.3 58.5 N.A. 44.5 53 47.9 N.A.
P-Site Identity: 100 100 6.6 53.3 N.A. 66.6 6.6 N.A. N.A. 20 0 6.6 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 33.3 60 N.A. 73.3 13.3 N.A. N.A. 26.6 26.6 20 N.A. 26.6 26.6 6.6 N.A.
Percent
Protein Identity: 33.1 N.A. N.A. 32.4 31.6 N.A.
Protein Similarity: 49.5 N.A. N.A. 48.9 49.1 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 14 7 20 0 0 20 14 0 7 7 14 14 27 % A
% Cys: 7 0 7 7 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 14 7 0 7 0 0 7 0 0 0 0 0 0 7 % D
% Glu: 14 20 0 0 7 7 0 0 27 0 0 0 0 0 7 % E
% Phe: 0 0 0 7 0 0 0 7 0 0 0 0 0 7 0 % F
% Gly: 7 0 7 0 0 0 7 14 0 0 7 0 20 20 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 7 0 7 14 14 0 0 0 0 0 0 7 0 % I
% Lys: 0 7 7 0 0 0 7 7 0 20 14 20 0 0 0 % K
% Leu: 7 0 20 14 14 40 7 0 7 20 7 0 0 14 7 % L
% Met: 7 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 20 7 0 14 0 7 0 7 0 7 14 0 % N
% Pro: 20 0 0 27 7 7 7 7 20 34 7 7 0 14 7 % P
% Gln: 0 14 0 7 0 7 0 0 0 0 27 0 34 0 20 % Q
% Arg: 7 40 0 7 7 0 14 14 7 7 20 7 0 7 7 % R
% Ser: 7 0 7 7 20 0 7 0 0 7 7 14 7 0 7 % S
% Thr: 0 0 14 0 0 0 20 20 0 14 0 40 14 0 0 % T
% Val: 7 7 14 0 0 27 0 7 20 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _