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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP85 All Species: 20.91
Human Site: S187 Identified Species: 41.82
UniProt: Q9BW27 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW27 NP_079120.1 656 75019 S187 L S A D V L G S E N P S K H D
Chimpanzee Pan troglodytes XP_511672 656 74927 S187 L S A D V L G S E N P S K H D
Rhesus Macaque Macaca mulatta XP_001093985 553 62963 D105 L V L Q G R L D E A R Q M L S
Dog Lupus familis XP_533121 655 74772 S187 L L A D V L G S E N P S K H E
Cat Felis silvestris
Mouse Mus musculus Q8R480 656 74758 G187 L S A D V L G G D N P S K H E
Rat Rattus norvegicus Q4QQS8 656 74863 S187 L S A D V L G S D H P S K H E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507008 624 70648 L166 A G P L L L L L L D W I R L H
Chicken Gallus gallus NP_001006426 674 77143 Q209 M V R E V L G Q R K S I K N T
Frog Xenopus laevis Q68FJ0 653 75054 S185 I V Q D V L R S E K P T E H E
Zebra Danio Brachydanio rerio Q6DBY0 649 74130 S185 R A R E V L Q S E N P T Q H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611300 668 76854 W172 V V P Q L L D W A R F H S P H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794718 718 81786 S240 D P G P D D E S T K S N G Y R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 78.1 91.6 N.A. 91.6 92.5 N.A. 73.1 72.2 68.4 65.2 N.A. 31.5 N.A. N.A. 39.2
Protein Similarity: 100 99.8 81 96 N.A. 96.4 96.8 N.A. 80.9 85.6 84.3 82.7 N.A. 53.5 N.A. N.A. 58.5
P-Site Identity: 100 100 13.3 86.6 N.A. 80 80 N.A. 6.6 26.6 46.6 46.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 100 N.A. 26.6 46.6 73.3 73.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 42 0 0 0 0 0 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 50 9 9 9 9 17 9 0 0 0 0 17 % D
% Glu: 0 0 0 17 0 0 9 0 50 0 0 0 9 0 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 9 9 0 9 0 50 9 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 9 0 59 17 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 25 0 0 50 0 0 % K
% Leu: 50 9 9 9 17 84 17 9 9 0 0 0 0 17 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 42 0 9 0 9 0 % N
% Pro: 0 9 17 9 0 0 0 0 0 0 59 0 0 9 9 % P
% Gln: 0 0 9 17 0 0 9 9 0 0 0 9 9 0 0 % Q
% Arg: 9 0 17 0 0 9 9 0 9 9 9 0 9 0 9 % R
% Ser: 0 34 0 0 0 0 0 59 0 0 17 42 9 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 0 17 0 0 9 % T
% Val: 9 34 0 0 67 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _