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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP85 All Species: 23.94
Human Site: S558 Identified Species: 47.88
UniProt: Q9BW27 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BW27 NP_079120.1 656 75019 S558 K R F A D A A S L L L S L M T
Chimpanzee Pan troglodytes XP_511672 656 74927 S558 K R F A D A A S L L L S L M T
Rhesus Macaque Macaca mulatta XP_001093985 553 62963 L456 A D A A S L L L S L M T S R I
Dog Lupus familis XP_533121 655 74772 S558 K R L A D A A S L L L S L M T
Cat Felis silvestris
Mouse Mus musculus Q8R480 656 74758 S558 K R F G D A A S L L L S L M T
Rat Rattus norvegicus Q4QQS8 656 74863 S558 K R F G D A A S L L L S L M T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507008 624 70648 I526 I D N L G S S I M L S D R L T
Chicken Gallus gallus NP_001006426 674 77143 S577 L Y G E K R F S E A A R L L L
Frog Xenopus laevis Q68FJ0 653 75054 S556 E Q F S E A A S L L L S L M T
Zebra Danio Brachydanio rerio Q6DBY0 649 74130 S552 L Y G E N R F S D A A K L L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611300 668 76854 E562 R D F L S A S E L L V N L L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794718 718 81786 A614 G D F S D A G A L L L S L L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 78.1 91.6 N.A. 91.6 92.5 N.A. 73.1 72.2 68.4 65.2 N.A. 31.5 N.A. N.A. 39.2
Protein Similarity: 100 99.8 81 96 N.A. 96.4 96.8 N.A. 80.9 85.6 84.3 82.7 N.A. 53.5 N.A. N.A. 58.5
P-Site Identity: 100 100 13.3 93.3 N.A. 93.3 93.3 N.A. 13.3 13.3 73.3 13.3 N.A. 33.3 N.A. N.A. 53.3
P-Site Similarity: 100 100 26.6 93.3 N.A. 93.3 93.3 N.A. 40 20 100 26.6 N.A. 66.6 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 34 0 67 50 9 0 17 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 0 0 50 0 0 0 9 0 0 9 0 0 0 % D
% Glu: 9 0 0 17 9 0 0 9 9 0 0 0 0 0 9 % E
% Phe: 0 0 59 0 0 0 17 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 17 17 9 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % I
% Lys: 42 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % K
% Leu: 17 0 9 17 0 9 9 9 67 84 59 0 84 42 17 % L
% Met: 0 0 0 0 0 0 0 0 9 0 9 0 0 50 0 % M
% Asn: 0 0 9 0 9 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 42 0 0 0 17 0 0 0 0 0 9 9 9 9 % R
% Ser: 0 0 0 17 17 9 17 67 9 0 9 59 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 59 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _