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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAT2
All Species:
27.58
Human Site:
S185
Identified Species:
67.41
UniProt:
Q9BWD1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWD1
NP_005882.2
397
41351
S185
Q
D
K
V
A
V
L
S
Q
N
R
T
E
N
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106967
397
41513
S185
Q
D
E
I
A
V
L
S
Q
N
R
T
E
N
T
Dog
Lupus familis
XP_541180
397
41084
S185
Q
D
K
C
A
V
L
S
Q
N
R
T
E
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAY6
397
41279
S185
Q
D
K
V
A
V
L
S
Q
N
R
A
E
H
A
Rat
Rattus norvegicus
Q5XI22
397
41090
S185
Q
D
K
V
A
V
V
S
Q
N
R
A
E
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU46
420
44109
S211
Q
D
S
F
A
I
H
S
Y
T
R
S
K
A
A
Zebra Danio
Brachydanio rerio
Q6AZA0
420
44324
Y212
D
A
F
A
I
K
S
Y
T
L
S
K
A
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198891
394
40735
S182
Q
D
Q
F
A
L
G
S
Q
L
K
A
E
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S4Y1
403
41393
S191
Q
D
D
Y
A
V
Q
S
F
E
R
G
I
A
A
Baker's Yeast
Sacchar. cerevisiae
P41338
398
41710
S185
Q
D
N
F
A
I
E
S
Y
Q
K
S
Q
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
88.1
N.A.
87.6
87.1
N.A.
N.A.
N.A.
40.4
42.1
N.A.
N.A.
N.A.
N.A.
63.2
Protein Similarity:
100
N.A.
93.1
92.6
N.A.
94.2
94.2
N.A.
N.A.
N.A.
60.2
60.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
N.A.
80
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
40
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
60
0
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
60
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
90
0
0
0
0
0
0
30
10
30
70
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
90
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
0
0
10
0
0
60
0
0
% E
% Phe:
0
0
10
30
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
10
10
20
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
40
0
0
10
0
0
0
0
20
10
10
20
0
% K
% Leu:
0
0
0
0
0
10
40
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
50
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
90
0
10
0
0
0
10
0
60
10
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
10
90
0
0
10
20
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
30
0
0
10
% T
% Val:
0
0
0
30
0
60
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
10
0
0
0
10
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _