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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAT2 All Species: 21.21
Human Site: S74 Identified Species: 51.85
UniProt: Q9BWD1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BWD1 NP_005882.2 397 41351 S74 Q N P V R Q A S V G A G I P Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106967 397 41513 S74 Q N P V R Q A S V G A G I P Y
Dog Lupus familis XP_541180 397 41084 S74 Q N P V R Q A S M G A G I P Y
Cat Felis silvestris
Mouse Mus musculus Q8CAY6 397 41279 S74 Q N P T R Q A S V G A G I P Y
Rat Rattus norvegicus Q5XI22 397 41090 S74 Q N P T R Q A S V G A G I P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6NU46 420 44109 A100 G Q A P S R Q A T L G A G L A
Zebra Danio Brachydanio rerio Q6AZA0 420 44324 L101 Q A P T R Q A L L G A G L P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198891 394 40735 S71 Q N P A R Q A S V N A G I P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8S4Y1 403 41393 L80 A P A R Q A A L G A G I P N S
Baker's Yeast Sacchar. cerevisiae P41338 398 41710 L74 A P A R Q V A L A A G L S N H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.6 88.1 N.A. 87.6 87.1 N.A. N.A. N.A. 40.4 42.1 N.A. N.A. N.A. N.A. 63.2
Protein Similarity: 100 N.A. 93.1 92.6 N.A. 94.2 94.2 N.A. N.A. N.A. 60.2 60.2 N.A. N.A. N.A. N.A. 75.8
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. 0 60 N.A. N.A. N.A. N.A. 80
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 13.3 73.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 46.4 42.2 N.A.
Protein Similarity: N.A. N.A. N.A. 61 60 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 30 10 0 10 90 10 10 20 70 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 60 30 70 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 60 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 30 10 10 0 10 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 60 0 0 0 0 0 0 0 10 0 0 0 20 0 % N
% Pro: 0 20 70 10 0 0 0 0 0 0 0 0 10 70 0 % P
% Gln: 70 10 0 0 20 70 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 20 70 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 0 60 0 0 0 0 10 0 10 % S
% Thr: 0 0 0 30 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 30 0 10 0 0 50 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _