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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAT2
All Species:
15.45
Human Site:
T275
Identified Species:
37.78
UniProt:
Q9BWD1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWD1
NP_005882.2
397
41351
T275
E
A
D
K
R
G
L
T
P
L
A
R
I
V
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106967
397
41513
T275
E
A
D
K
R
G
L
T
P
L
A
R
I
V
S
Dog
Lupus familis
XP_541180
397
41084
T275
E
A
A
N
R
G
L
T
P
L
A
Q
I
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAY6
397
41279
K275
E
A
E
R
R
M
L
K
P
L
A
R
I
V
S
Rat
Rattus norvegicus
Q5XI22
397
41090
K275
E
A
E
S
R
M
L
K
P
L
A
Q
V
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU46
420
44109
T300
A
A
N
R
L
N
V
T
P
L
A
R
I
V
A
Zebra Danio
Brachydanio rerio
Q6AZA0
420
44324
T300
A
A
Q
R
L
N
V
T
P
L
A
K
I
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198891
394
40735
A272
E
A
Q
K
R
G
V
A
P
L
A
R
I
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S4Y1
403
41393
L281
K
A
L
Q
L
G
L
L
V
L
A
K
I
K
G
Baker's Yeast
Sacchar. cerevisiae
P41338
398
41710
K275
V
L
K
E
K
N
L
K
P
L
A
I
I
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
88.1
N.A.
87.6
87.1
N.A.
N.A.
N.A.
40.4
42.1
N.A.
N.A.
N.A.
N.A.
63.2
Protein Similarity:
100
N.A.
93.1
92.6
N.A.
94.2
94.2
N.A.
N.A.
N.A.
60.2
60.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
N.A.
100
80
N.A.
73.3
60
N.A.
N.A.
N.A.
53.3
46.6
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
80
73.3
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
60
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
90
10
0
0
0
0
10
0
0
100
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
60
0
20
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
90
0
0
% I
% Lys:
10
0
10
30
10
0
0
30
0
0
0
20
0
20
0
% K
% Leu:
0
10
10
0
30
0
70
10
0
100
0
0
0
0
0
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
30
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% P
% Gln:
0
0
20
10
0
0
0
0
0
0
0
20
0
0
0
% Q
% Arg:
0
0
0
30
60
0
0
0
0
0
0
50
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
60
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
30
0
10
0
0
0
10
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _