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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAT2
All Species:
5.15
Human Site:
T46
Identified Species:
12.59
UniProt:
Q9BWD1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWD1
NP_005882.2
397
41351
T46
K
E
V
L
K
R
A
T
V
A
P
E
D
V
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106967
397
41513
T46
K
E
D
L
K
R
A
T
V
V
P
E
D
V
W
Dog
Lupus familis
XP_541180
397
41084
A46
K
E
V
L
R
R
A
A
V
A
P
E
E
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAY6
397
41279
K46
K
E
V
L
Q
R
A
K
V
A
P
E
E
V
S
Rat
Rattus norvegicus
Q5XI22
397
41090
K46
K
E
V
L
Q
R
A
K
V
A
P
E
E
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU46
420
44109
G73
K
A
A
V
E
R
A
G
I
P
A
D
E
V
K
Zebra Danio
Brachydanio rerio
Q6AZA0
420
44324
G73
K
G
A
I
D
K
A
G
I
P
V
E
E
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198891
394
40735
S47
Q
R
S
G
V
S
S
S
D
V
S
E
V
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S4Y1
403
41393
N51
A
A
A
L
K
R
A
N
V
D
P
A
L
V
Q
Baker's Yeast
Sacchar. cerevisiae
P41338
398
41710
F51
E
L
D
A
S
K
D
F
D
E
I
I
F
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
88.1
N.A.
87.6
87.1
N.A.
N.A.
N.A.
40.4
42.1
N.A.
N.A.
N.A.
N.A.
63.2
Protein Similarity:
100
N.A.
93.1
92.6
N.A.
94.2
94.2
N.A.
N.A.
N.A.
60.2
60.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
N.A.
80
80
N.A.
80
80
N.A.
N.A.
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
80
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
60
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
60
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
30
10
0
0
80
10
0
40
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
10
0
10
0
20
10
0
10
20
0
0
% D
% Glu:
10
50
0
0
10
0
0
0
0
10
0
70
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
10
0
0
0
20
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
20
0
10
10
0
10
0
% I
% Lys:
70
0
0
0
30
20
0
20
0
0
0
0
0
0
20
% K
% Leu:
0
10
0
60
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
20
60
0
0
0
0
% P
% Gln:
10
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
10
70
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
10
10
10
0
0
10
0
0
0
40
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
0
40
10
10
0
0
0
60
20
10
0
10
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _