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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAT2
All Species:
18.48
Human Site:
Y237
Identified Species:
45.19
UniProt:
Q9BWD1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWD1
NP_005882.2
397
41351
Y237
A
M
S
K
L
K
P
Y
F
L
T
D
G
T
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106967
397
41513
Y237
A
M
S
T
L
K
P
Y
F
L
T
D
G
M
G
Dog
Lupus familis
XP_541180
397
41084
Y237
A
V
S
K
L
K
P
Y
F
L
T
D
G
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAY6
397
41279
Y237
A
M
G
K
L
K
P
Y
F
L
T
D
G
T
G
Rat
Rattus norvegicus
Q5XI22
397
41090
Y237
A
M
S
K
L
K
P
Y
F
L
T
D
G
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU46
420
44109
T262
S
K
F
P
K
L
K
T
V
F
Q
K
D
N
G
Zebra Danio
Brachydanio rerio
Q6AZA0
420
44324
A262
S
K
V
P
K
L
K
A
V
F
L
K
E
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198891
394
40735
C234
G
M
T
K
L
R
S
C
F
I
K
D
A
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S4Y1
403
41393
P243
A
K
L
R
K
L
R
P
S
F
K
E
N
G
G
Baker's Yeast
Sacchar. cerevisiae
P41338
398
41710
T237
E
K
L
R
S
A
R
T
V
F
Q
K
E
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90.6
88.1
N.A.
87.6
87.1
N.A.
N.A.
N.A.
40.4
42.1
N.A.
N.A.
N.A.
N.A.
63.2
Protein Similarity:
100
N.A.
93.1
92.6
N.A.
94.2
94.2
N.A.
N.A.
N.A.
60.2
60.2
N.A.
N.A.
N.A.
N.A.
75.8
P-Site Identity:
100
N.A.
86.6
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
N.A.
86.6
100
N.A.
93.3
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
60
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
0
10
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
60
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
20
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
60
40
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
50
10
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
40
0
50
30
50
20
0
0
0
20
30
0
0
0
% K
% Leu:
0
0
20
0
60
30
0
0
0
50
10
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
30
0
% N
% Pro:
0
0
0
20
0
0
50
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
0
20
0
10
20
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
40
0
10
0
10
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
0
0
0
20
0
0
50
0
0
50
0
% T
% Val:
0
10
10
0
0
0
0
0
30
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _