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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFXN3 All Species: 13.64
Human Site: T219 Identified Species: 25
UniProt: Q9BWM7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BWM7 NP_112233.2 321 35503 T219 Q R L G Y S V T A A K Q G I F
Chimpanzee Pan troglodytes XP_001169538 325 35978 T223 Q R L G Y S V T A A K Q G I F
Rhesus Macaque Macaca mulatta XP_001101646 304 33663 G203 R Q R H E L L G P V P D F D S
Dog Lupus familis XP_543977 321 35507 A219 Q R L G H S V A A A K Q G I F
Cat Felis silvestris
Mouse Mus musculus Q91V61 321 35388 T219 Q R L G H S V T A A K Q G I F
Rat Rattus norvegicus Q9JHY2 321 35415 T219 Q R L G H S V T A A K Q G I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511523 322 35745 K220 N R L G E S A K A A Q Q A I T
Chicken Gallus gallus XP_414544 322 35657 K220 N R L G E S T K A A Q Q A I T
Frog Xenopus laevis NP_001090349 322 35633 N220 N R I G E S A N A A K Q A I T
Zebra Danio Brachydanio rerio NP_001074133 322 35308 N220 K R L G E S T N A A Q Q A I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09201 329 36736 K223 Q L V G K S Q K M A A L S I A
Sea Urchin Strong. purpuratus XP_794780 334 36713 K232 H R L G N S K K A A K S A I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12029 327 35396 K225 D E V G K S K K A A F M A V G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 86.9 94.3 N.A. 93.7 93.4 N.A. 75.7 77.3 77.6 76 N.A. N.A. N.A. 46.8 59.5
Protein Similarity: 100 98.4 90 97.1 N.A. 97.5 97.5 N.A. 86 88.5 87.2 86 N.A. N.A. N.A. 64.7 73.9
P-Site Identity: 100 100 0 86.6 N.A. 93.3 93.3 N.A. 53.3 53.3 53.3 53.3 N.A. N.A. N.A. 33.3 53.3
P-Site Similarity: 100 100 20 93.3 N.A. 100 100 N.A. 60 60 60 66.6 N.A. N.A. N.A. 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 8 85 93 8 0 47 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % D
% Glu: 0 8 0 0 39 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 39 % F
% Gly: 0 0 0 93 0 0 0 8 0 0 0 0 39 0 8 % G
% His: 8 0 0 8 24 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 85 0 % I
% Lys: 8 0 0 0 16 0 16 39 0 0 54 0 0 0 0 % K
% Leu: 0 8 70 0 0 8 8 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % M
% Asn: 24 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % P
% Gln: 47 8 0 0 0 0 8 0 0 0 24 70 0 0 0 % Q
% Arg: 8 77 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 93 0 0 0 0 0 8 8 0 8 % S
% Thr: 0 0 0 0 0 0 16 31 0 0 0 0 0 0 31 % T
% Val: 0 0 16 0 0 0 39 0 0 8 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _