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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDCA7
All Species:
9.09
Human Site:
S226
Identified Species:
16.67
UniProt:
Q9BWT1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWT1
NP_114148.3
371
42573
S226
N
E
D
D
L
P
R
S
R
R
S
R
S
S
V
Chimpanzee
Pan troglodytes
XP_515914
533
60419
S388
N
E
D
D
L
P
R
S
R
R
S
R
S
S
V
Rhesus Macaque
Macaca mulatta
XP_001086468
371
42534
S226
N
E
D
D
L
P
R
S
R
R
S
R
S
S
M
Dog
Lupus familis
XP_545525
486
55132
P340
Y
M
N
E
D
D
M
P
R
S
R
R
A
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M2
382
43819
R237
M
N
D
D
D
V
P
R
S
R
R
P
G
S
M
Rat
Rattus norvegicus
Q4KM91
377
43006
R232
M
N
D
D
D
V
S
R
S
R
R
P
G
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514776
497
56107
R352
L
E
E
D
Q
G
P
R
R
G
R
P
G
T
M
Chicken
Gallus gallus
XP_423365
410
46348
R265
E
H
D
A
Q
T
P
R
R
G
H
R
G
A
M
Frog
Xenopus laevis
NP_001091283
440
49730
R293
E
D
E
D
Y
K
P
R
K
R
F
S
S
V
H
Zebra Danio
Brachydanio rerio
NP_001017574
394
44585
R249
E
E
E
K
E
P
R
R
R
S
Y
N
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121657
298
34518
D173
P
D
N
I
P
S
V
D
E
I
T
D
E
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188312
245
27839
H120
P
T
Y
N
A
P
R
H
P
D
D
I
T
E
E
Poplar Tree
Populus trichocarpa
XP_002310169
241
27487
R116
K
L
L
G
N
T
E
R
S
W
T
L
F
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.8
98.3
67.2
N.A.
82.7
83.8
N.A.
56.1
55.8
51.3
52.7
N.A.
N.A.
30.1
N.A.
32.8
Protein Similarity:
100
69.4
99.1
72
N.A.
88.4
89.3
N.A.
63.1
68
63.4
63.9
N.A.
N.A.
46.6
N.A.
44.7
P-Site Identity:
100
100
93.3
13.3
N.A.
26.6
26.6
N.A.
20
20
20
40
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
33.3
N.A.
40
33.3
40
53.3
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
27.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
47
54
24
8
0
8
0
8
8
8
0
0
8
% D
% Glu:
24
39
24
8
8
0
8
0
8
0
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
16
0
0
31
8
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
24
0
0
0
0
0
0
8
0
0
16
% L
% Met:
16
8
0
0
0
0
8
0
0
0
0
0
0
8
39
% M
% Asn:
24
16
16
8
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
16
0
0
0
8
39
31
8
8
0
0
24
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
39
54
54
47
31
39
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
24
24
16
24
8
39
47
8
% S
% Thr:
0
8
0
0
0
16
0
0
0
0
16
0
8
8
0
% T
% Val:
0
0
0
0
0
16
8
0
0
0
0
0
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _