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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLG All Species: 10.61
Human Site: T594 Identified Species: 19.44
UniProt: Q9BWT3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BWT3 NP_075045.2 736 82803 T594 I G A K V D S T V K T V S P P
Chimpanzee Pan troglodytes XP_515496 714 80108 K572 P A A V I V E K P L S V P P A
Rhesus Macaque Macaca mulatta XP_001115228 736 82662 T594 I G A K V D S T V K A V S P P
Dog Lupus familis XP_852387 738 83115 A594 L S I P V I G A K V D S A V K
Cat Felis silvestris
Mouse Mus musculus Q6PCL9 739 82938 T597 I G A K V D P T A K A V S S P
Rat Rattus norvegicus NP_001100714 739 82781 A597 I G A K G D A A V K A V S S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 I592 G G S S S E S I P Q T A T Q P
Chicken Gallus gallus XP_421352 737 82879 I594 G G S S N E S I P Q T A T Q P
Frog Xenopus laevis P51004 715 80169 S574 L G G S L N E S I P E S A T H
Zebra Danio Brachydanio rerio NP_956915 744 82994 I595 K P E Q G M S I P V I G S K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 S474 L R Q A E Q L S M L K E G M W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780989 670 74465 K529 G D D A Q T F K R P S S P P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 K427 D Y E M I Q D K Y G S H K T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 98.2 94.8 N.A. 93.9 93.3 N.A. 59.7 60.5 57.2 74.8 N.A. N.A. 49.3 N.A. 50.2
Protein Similarity: 100 97 99 96.3 N.A. 96.2 96 N.A. 71.5 73.2 71.7 85.7 N.A. N.A. 63.3 N.A. 66.8
P-Site Identity: 100 20 93.3 6.6 N.A. 73.3 66.6 N.A. 26.6 26.6 6.6 20 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 33.3 93.3 20 N.A. 73.3 73.3 N.A. 53.3 53.3 46.6 26.6 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 39 16 0 0 8 16 8 0 24 16 16 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 31 8 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 16 0 8 16 16 0 0 0 8 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 24 54 8 0 16 0 8 0 0 8 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 31 0 8 0 16 8 0 24 8 0 8 0 0 0 0 % I
% Lys: 8 0 0 31 0 0 0 24 8 31 8 0 8 8 8 % K
% Leu: 24 0 0 0 8 0 8 0 0 16 0 0 0 0 0 % L
% Met: 0 0 0 8 0 8 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 0 8 0 31 16 0 0 16 31 62 % P
% Gln: 0 0 8 8 8 16 0 0 0 16 0 0 0 16 0 % Q
% Arg: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 8 16 24 8 0 39 16 0 0 24 24 39 16 0 % S
% Thr: 0 0 0 0 0 8 0 24 0 0 24 0 16 16 0 % T
% Val: 0 0 0 8 31 8 0 0 24 16 0 39 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _