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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLG All Species: 15.76
Human Site: T654 Identified Species: 28.89
UniProt: Q9BWT3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BWT3 NP_075045.2 736 82803 T654 H S P S I D G T P K R L K D V
Chimpanzee Pan troglodytes XP_515496 714 80108 N632 A Q G Q P H L N G M S N I T K
Rhesus Macaque Macaca mulatta XP_001115228 736 82662 T654 H S P S I D G T P K R L K D I
Dog Lupus familis XP_852387 738 83115 I654 K R S H S P S I D G S S K R L
Cat Felis silvestris
Mouse Mus musculus Q6PCL9 739 82938 T657 H S P P T D G T S K R L K D I
Rat Rattus norvegicus NP_001100714 739 82781 T657 H S P P T D G T A K R L K D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 P652 S P N K E E S P K K T K T E E
Chicken Gallus gallus XP_421352 737 82879 P654 S P H K E D S P K K M K I E E
Frog Xenopus laevis P51004 715 80169 S634 S S P S N E D S P K K N K T E
Zebra Danio Brachydanio rerio NP_956915 744 82994 E655 R P H S P S L E D P P K R H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 T534 S P R N P G N T T N R K R L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780989 670 74465 E589 S S P I P V L E S P P K K M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 E487 D I H I P C T E F V N L C R S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 98.2 94.8 N.A. 93.9 93.3 N.A. 59.7 60.5 57.2 74.8 N.A. N.A. 49.3 N.A. 50.2
Protein Similarity: 100 97 99 96.3 N.A. 96.2 96 N.A. 71.5 73.2 71.7 85.7 N.A. N.A. 63.3 N.A. 66.8
P-Site Identity: 100 0 93.3 6.6 N.A. 73.3 73.3 N.A. 6.6 13.3 40 6.6 N.A. N.A. 13.3 N.A. 20
P-Site Similarity: 100 0 100 13.3 N.A. 80 80 N.A. 20 20 60 13.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 34.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 0 0 0 39 8 0 16 0 0 0 0 31 0 % D
% Glu: 0 0 0 0 16 16 0 24 0 0 0 0 0 16 24 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 8 31 0 8 8 0 0 0 0 0 % G
% His: 31 0 24 8 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 16 16 0 0 8 0 0 0 0 16 0 24 % I
% Lys: 8 0 0 16 0 0 0 0 16 54 8 39 54 0 24 % K
% Leu: 0 0 0 0 0 0 24 0 0 0 0 39 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 0 0 8 8 8 0 8 8 0 8 8 16 0 0 0 % N
% Pro: 0 31 47 16 39 8 0 16 24 16 16 0 0 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 8 0 0 0 0 0 0 0 39 0 16 16 0 % R
% Ser: 39 47 8 31 8 8 24 8 16 0 16 8 0 0 16 % S
% Thr: 0 0 0 0 16 0 8 39 8 0 8 0 8 16 0 % T
% Val: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _