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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK19
All Species:
17.58
Human Site:
S490
Identified Species:
35.15
UniProt:
Q9BWU1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWU1
NP_055891.1
502
56802
S490
Y
S
S
S
S
Q
Q
S
S
Q
Y
H
P
S
H
Chimpanzee
Pan troglodytes
XP_001146708
601
67560
S589
Y
S
S
S
S
Q
Q
S
S
Q
Y
H
P
S
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855153
466
52441
S454
Y
S
S
S
S
Q
Q
S
T
Q
Y
H
P
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWD8
501
56552
T490
Y
S
S
S
Q
Q
S
T
Q
Y
H
S
S
H
Q
Rat
Rattus norvegicus
NP_001101104
501
56595
T490
Y
S
S
S
Q
Q
S
T
Q
Y
H
P
S
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516816
464
53235
Q453
G
Y
S
T
T
S
Q
Q
P
P
Q
Y
S
H
Q
Chicken
Gallus gallus
XP_419786
620
69430
S608
Y
S
T
S
S
Q
Q
S
S
Q
Y
H
Q
S
H
Frog
Xenopus laevis
Q66KH9
416
47745
Q405
G
Y
T
S
T
S
Q
Q
P
P
Q
Y
S
H
Q
Zebra Danio
Brachydanio rerio
Q8JH47
464
53215
Q453
G
Y
S
S
T
S
Q
Q
P
P
Q
Y
S
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT57
454
53663
M442
Q
Q
Q
Q
Q
Q
Q
M
M
F
N
Q
Q
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90866
588
67767
Q533
A
V
P
G
P
G
P
Q
G
Y
M
N
P
Q
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TI6
470
52779
M458
R
K
D
P
G
M
G
M
S
G
Y
A
P
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
N.A.
89.8
N.A.
96.4
96.4
N.A.
77.4
76.7
68.1
76.6
N.A.
67.3
N.A.
46.9
N.A.
Protein Similarity:
100
81.1
N.A.
90.8
N.A.
97.2
97.2
N.A.
83.4
78.3
74
82.6
N.A.
74.5
N.A.
60.3
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
33.3
33.3
N.A.
13.3
86.6
13.3
20
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
46.6
46.6
N.A.
33.3
93.3
33.3
33.3
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
25
0
0
9
9
9
9
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
17
34
0
42
34
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
17
9
0
9
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
17
% N
% Pro:
0
0
9
9
9
0
9
0
25
25
0
9
42
9
0
% P
% Gln:
9
9
9
9
25
59
67
34
17
34
25
9
17
17
42
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
59
67
34
25
17
34
34
0
0
9
42
34
0
% S
% Thr:
0
0
17
9
25
0
0
17
9
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
25
0
0
0
0
0
0
0
25
42
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _