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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK19
All Species:
28.18
Human Site:
Y276
Identified Species:
56.36
UniProt:
Q9BWU1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWU1
NP_055891.1
502
56802
Y276
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Chimpanzee
Pan troglodytes
XP_001146708
601
67560
Y375
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855153
466
52441
Y240
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWD8
501
56552
Y276
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Rat
Rattus norvegicus
NP_001101104
501
56595
Y276
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516816
464
53235
Y247
D
I
K
T
S
N
P
Y
H
H
D
Q
L
D
R
Chicken
Gallus gallus
XP_419786
620
69430
Y394
D
I
R
K
M
P
E
Y
P
T
L
Q
K
D
F
Frog
Xenopus laevis
Q66KH9
416
47745
H210
E
L
L
L
G
A
R
H
Y
T
K
A
I
D
K
Zebra Danio
Brachydanio rerio
Q8JH47
464
53215
Y247
D
I
K
T
S
N
P
Y
H
H
D
Q
L
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT57
454
53663
Y247
D
I
K
T
S
N
P
Y
H
H
D
Q
L
D
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90866
588
67767
L289
M
P
D
H
Q
R
L
L
S
D
A
R
N
E
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TI6
470
52779
P263
I
F
K
I
L
G
H
P
T
M
D
K
W
P
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
N.A.
89.8
N.A.
96.4
96.4
N.A.
77.4
76.7
68.1
76.6
N.A.
67.3
N.A.
46.9
N.A.
Protein Similarity:
100
81.1
N.A.
90.8
N.A.
97.2
97.2
N.A.
83.4
78.3
74
82.6
N.A.
74.5
N.A.
60.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
33.3
100
13.3
33.3
N.A.
33.3
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
40
100
33.3
40
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
9
0
0
0
0
0
0
9
34
0
0
84
0
% D
% Glu:
9
0
0
0
0
0
50
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
50
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
9
0
0
9
9
25
25
0
0
0
0
0
% H
% Ile:
9
75
0
9
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
34
50
0
0
0
0
0
0
9
9
50
0
9
% K
% Leu:
0
9
9
9
9
0
9
9
0
0
50
0
25
0
0
% L
% Met:
9
0
0
0
50
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
50
25
9
50
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
75
0
0
0
% Q
% Arg:
0
0
50
0
0
9
9
0
0
0
0
9
0
0
25
% R
% Ser:
0
0
0
0
25
0
0
0
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
25
0
0
0
0
9
59
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _