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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL2
All Species:
5.15
Human Site:
S538
Identified Species:
14.17
UniProt:
Q9BWV7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWV7
NP_114155.4
592
67237
S538
H
S
C
K
T
K
T
S
P
C
V
L
S
D
R
Chimpanzee
Pan troglodytes
XP_527569
587
66894
S533
H
S
C
K
T
K
T
S
P
C
V
L
S
D
H
Rhesus Macaque
Macaca mulatta
XP_001082070
525
60392
G487
K
A
P
D
P
Q
A
G
N
F
V
L
V
F
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9E4
540
62091
D502
E
A
G
S
T
P
N
D
H
A
G
N
F
V
L
Rat
Rattus norvegicus
Q5PPI9
423
49122
E385
Y
E
I
L
Y
D
E
E
L
A
Q
G
D
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419607
550
62958
F509
V
G
G
F
V
L
I
F
P
F
N
E
A
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104700
577
65785
F528
T
N
R
L
A
S
S
F
N
A
N
E
R
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
T789
I
T
Q
L
L
S
A
T
H
K
R
N
T
G
G
Honey Bee
Apis mellifera
XP_624352
482
56370
P444
N
G
K
D
W
S
K
P
C
T
T
A
K
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
83.9
N.A.
N.A.
61.9
24.1
N.A.
N.A.
48.4
N.A.
40.2
N.A.
20.3
33.1
N.A.
N.A.
Protein Similarity:
100
89.8
85.6
N.A.
N.A.
72.1
39.1
N.A.
N.A.
63
N.A.
56.2
N.A.
35.1
47.1
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
N.A.
N.A.
6.6
0
N.A.
N.A.
6.6
N.A.
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
N.A.
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
20
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
12
0
23
0
0
34
0
12
12
12
12
% A
% Cys:
0
0
23
0
0
0
0
0
12
23
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
12
0
12
0
0
0
0
12
23
0
% D
% Glu:
12
12
0
0
0
0
12
12
0
0
0
23
0
12
0
% E
% Phe:
0
0
0
12
0
0
0
23
0
23
0
0
12
12
0
% F
% Gly:
0
23
23
0
0
0
0
12
0
0
12
12
0
23
12
% G
% His:
23
0
0
0
0
0
0
0
23
0
0
0
0
0
12
% H
% Ile:
12
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
23
0
23
12
0
0
12
0
0
12
0
12
% K
% Leu:
0
0
0
34
12
12
0
0
12
0
0
34
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
12
12
0
0
0
0
12
0
23
0
23
23
0
0
0
% N
% Pro:
0
0
12
0
12
12
0
12
34
0
0
0
0
0
12
% P
% Gln:
0
0
12
0
0
12
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
12
0
12
0
12
% R
% Ser:
0
23
0
12
0
34
12
23
0
0
0
0
23
0
0
% S
% Thr:
12
12
0
0
34
0
23
12
0
12
12
0
12
0
0
% T
% Val:
12
0
0
0
12
0
0
0
0
0
34
0
12
12
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _