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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOL6
All Species:
4.55
Human Site:
T251
Identified Species:
25
UniProt:
Q9BWW8
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BWW8
NP_085144.1
343
38128
T251
S
L
G
Y
D
L
A
T
L
S
K
E
W
K
H
Chimpanzee
Pan troglodytes
XP_525581
411
45064
Y281
D
E
E
E
K
A
D
Y
V
T
A
T
G
K
I
Rhesus Macaque
Macaca mulatta
XP_001082307
300
32964
Q219
V
S
S
R
S
S
R
Q
I
Q
K
A
F
G
G
Dog
Lupus familis
XP_538403
394
43847
T274
S
L
H
G
D
L
T
T
L
L
R
N
W
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6B959
246
26810
Y166
M
A
L
Y
N
S
V
Y
F
I
V
F
F
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
68.5
39.5
N.A.
N.A.
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70
74.9
54.8
N.A.
N.A.
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
53.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
60
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
20
20
0
0
0
20
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
40
0
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
20
20
0
0
0
0
0
0
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
20
0
0
20
40
0
0
% F
% Gly:
0
0
20
20
0
0
0
0
0
0
0
0
20
40
20
% G
% His:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
20
20
0
0
0
0
20
% I
% Lys:
0
0
0
0
20
0
0
0
0
0
40
0
0
60
0
% K
% Leu:
0
40
20
0
0
40
0
0
40
20
0
0
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
20
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
20
0
20
0
0
0
0
20
% Q
% Arg:
0
0
0
20
0
0
20
0
0
0
20
0
0
0
0
% R
% Ser:
40
20
20
0
20
40
0
0
0
20
0
0
0
0
20
% S
% Thr:
0
0
0
0
0
0
20
40
0
20
0
20
0
0
0
% T
% Val:
20
0
0
0
0
0
20
0
20
0
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% W
% Tyr:
0
0
0
40
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _