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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRIP1
All Species:
13.64
Human Site:
Y743
Identified Species:
27.27
UniProt:
Q9BX63
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX63
NP_114432.1
1249
140878
Y743
D
E
L
L
Q
V
Y
Y
D
A
I
K
Y
K
G
Chimpanzee
Pan troglodytes
XP_511607
1249
141020
Y743
D
E
L
L
Q
V
Y
Y
D
A
I
K
Y
K
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852649
1214
137064
Y742
N
E
L
L
Q
V
Y
Y
D
A
I
K
Y
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SXJ3
1174
131342
R710
L
L
E
K
L
R
E
R
W
I
F
T
G
L
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q3YK19
1252
140086
Y753
D
E
L
L
K
I
Y
Y
D
A
I
K
F
K
G
Frog
Xenopus laevis
NP_001083272
713
81026
K249
K
E
N
G
E
K
P
K
V
P
K
I
F
F
G
Zebra Danio
Brachydanio rerio
P0C928
1177
132786
C710
D
Y
G
A
I
F
L
C
D
H
R
F
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
P521
V
K
I
I
G
T
G
P
D
R
Q
Q
L
I
S
Honey Bee
Apis mellifera
XP_396001
928
106015
Q464
F
S
P
G
F
S
M
Q
Q
L
K
N
Q
G
A
Nematode Worm
Caenorhab. elegans
Q93575
994
112926
R530
V
L
T
S
I
V
T
R
G
K
R
G
G
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300637
1183
131692
I716
H
K
F
D
Y
G
S
I
I
L
L
D
E
R
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173495
1175
131597
G710
K
S
S
K
S
L
L
G
G
S
E
W
Y
C
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
81.5
N.A.
70.3
N.A.
N.A.
N.A.
56.5
35.2
24.2
N.A.
24.4
24.8
23.2
N.A.
Protein Similarity:
100
99.8
N.A.
88
N.A.
79.9
N.A.
N.A.
N.A.
70.4
44.2
42
N.A.
42.5
43
41.7
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
0
N.A.
N.A.
N.A.
80
13.3
13.3
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
0
N.A.
N.A.
N.A.
100
26.6
13.3
N.A.
33.3
0
6.6
N.A.
Percent
Protein Identity:
27.7
N.A.
N.A.
29.6
N.A.
N.A.
Protein Similarity:
46.8
N.A.
N.A.
47
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
34
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% C
% Asp:
34
0
0
9
0
0
0
0
50
0
0
9
0
0
0
% D
% Glu:
0
42
9
0
9
0
9
0
0
0
9
0
9
0
0
% E
% Phe:
9
0
9
0
9
9
0
0
0
0
9
9
17
9
0
% F
% Gly:
0
0
9
17
9
9
9
9
17
0
0
9
17
9
42
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
9
17
9
0
9
9
9
34
9
0
9
0
% I
% Lys:
17
17
0
17
9
9
0
9
0
9
17
34
9
34
0
% K
% Leu:
9
17
34
34
9
9
17
0
0
17
9
0
9
17
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
9
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
25
0
0
9
9
0
9
9
9
0
9
% Q
% Arg:
0
0
0
0
0
9
0
17
0
9
17
0
0
9
0
% R
% Ser:
0
17
9
9
9
9
9
0
0
9
0
0
0
9
9
% S
% Thr:
0
0
9
0
0
9
9
0
0
0
0
9
0
0
0
% T
% Val:
17
0
0
0
0
34
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
9
% W
% Tyr:
0
9
0
0
9
0
34
34
0
0
0
0
34
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _