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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HINT2
All Species:
5.76
Human Site:
T47
Identified Species:
10.56
UniProt:
Q9BX68
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX68
NP_115982.1
163
17162
T47
V
A
K
A
Q
Q
A
T
P
G
G
A
A
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084633
163
17199
T47
V
A
K
A
Q
Q
A
T
P
G
G
A
A
P
T
Dog
Lupus familis
XP_538721
326
34386
A210
V
T
K
A
Q
Q
A
A
P
R
G
A
A
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0S9
163
17302
A47
V
A
K
A
Q
K
A
A
P
G
G
A
S
P
T
Rat
Rattus norvegicus
NP_001101425
163
17362
V47
V
A
K
A
Q
K
A
V
P
G
G
A
A
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990020
126
13740
C38
I
I
Y
E
D
E
Q
C
L
A
F
H
D
I
S
Frog
Xenopus laevis
NP_001084557
177
19421
R61
Q
R
E
A
A
R
N
R
V
S
P
T
S
P
T
Zebra Danio
Brachydanio rerio
NP_001077041
161
17945
K45
L
A
Q
E
A
S
K
K
Y
G
K
L
E
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608711
150
16578
T34
S
E
V
E
K
S
Q
T
A
A
A
S
E
D
T
Honey Bee
Apis mellifera
XP_625049
204
22985
V88
T
E
V
E
K
A
Q
V
A
V
P
T
G
D
T
Nematode Worm
Caenorhab. elegans
P53795
130
14224
I35
R
K
E
I
P
A
K
I
I
F
E
D
D
E
A
Sea Urchin
Strong. purpuratus
XP_001193012
139
15498
K38
V
F
T
K
I
I
N
K
E
I
P
A
D
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42856
128
14282
E36
S
T
V
V
Y
E
D
E
K
V
L
A
F
R
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
46
N.A.
85.8
85.2
N.A.
N.A.
47.8
53.6
55.8
N.A.
51.5
41.1
43.5
49
Protein Similarity:
100
N.A.
97.5
48.1
N.A.
94.4
93.8
N.A.
N.A.
63.7
66.6
70.5
N.A.
66.2
60.2
60.7
65
P-Site Identity:
100
N.A.
100
80
N.A.
80
86.6
N.A.
N.A.
0
20
26.6
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
N.A.
100
80
N.A.
93.3
93.3
N.A.
N.A.
20
40
40
N.A.
26.6
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
43.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
60.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
0
47
16
16
39
16
16
16
8
54
31
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
8
24
16
8
% D
% Glu:
0
16
16
31
0
16
0
8
8
0
8
0
16
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
39
39
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
8
0
8
8
8
0
8
8
8
0
0
0
16
8
% I
% Lys:
0
8
39
8
16
16
16
16
8
0
8
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
39
0
24
0
0
54
0
% P
% Gln:
8
0
8
0
39
24
24
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
8
0
8
0
8
0
0
0
8
0
% R
% Ser:
16
0
0
0
0
16
0
0
0
8
0
8
16
0
8
% S
% Thr:
8
16
8
0
0
0
0
24
0
0
0
16
0
0
70
% T
% Val:
47
0
24
8
0
0
0
16
8
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _