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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HINT2
All Species:
36.36
Human Site:
Y131
Identified Species:
66.67
UniProt:
Q9BX68
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX68
NP_115982.1
163
17162
Y131
A
E
G
L
G
D
G
Y
R
L
V
I
N
D
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084633
163
17199
Y131
A
E
G
L
G
D
G
Y
R
L
V
I
N
D
G
Dog
Lupus familis
XP_538721
326
34386
Y294
A
E
G
L
G
D
G
Y
R
L
V
I
N
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0S9
163
17302
Y131
A
Q
G
L
K
D
G
Y
R
L
V
V
N
D
G
Rat
Rattus norvegicus
NP_001101425
163
17362
Y131
A
E
G
L
K
D
G
Y
R
L
V
V
N
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990020
126
13740
G104
V
L
N
E
G
P
E
G
G
Q
S
V
Y
H
V
Frog
Xenopus laevis
NP_001084557
177
19421
Y145
K
E
G
L
A
D
G
Y
R
L
V
I
N
D
G
Zebra Danio
Brachydanio rerio
NP_001077041
161
17945
Y129
K
E
G
L
A
E
G
Y
R
V
V
I
N
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608711
150
16578
Y118
E
L
G
L
A
D
G
Y
R
V
V
I
N
N
G
Honey Bee
Apis mellifera
XP_625049
204
22985
F172
Q
Q
G
L
D
N
G
F
R
L
V
I
N
D
G
Nematode Worm
Caenorhab. elegans
P53795
130
14224
Y98
Q
L
G
M
A
N
G
Y
R
V
V
V
N
N
G
Sea Urchin
Strong. purpuratus
XP_001193012
139
15498
Y107
K
E
P
L
E
D
G
Y
R
V
V
I
N
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P42856
128
14282
P104
R
V
V
I
N
D
G
P
S
G
C
Q
S
V
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
46
N.A.
85.8
85.2
N.A.
N.A.
47.8
53.6
55.8
N.A.
51.5
41.1
43.5
49
Protein Similarity:
100
N.A.
97.5
48.1
N.A.
94.4
93.8
N.A.
N.A.
63.7
66.6
70.5
N.A.
66.2
60.2
60.7
65
P-Site Identity:
100
N.A.
100
100
N.A.
80
86.6
N.A.
N.A.
6.6
86.6
73.3
N.A.
66.6
66.6
46.6
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
86.6
86.6
N.A.
80
86.6
80
80
Percent
Protein Identity:
N.A.
43.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
60.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
8
70
0
0
0
0
0
0
0
62
0
% D
% Glu:
8
54
0
8
8
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
31
0
93
8
8
8
0
0
0
0
85
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
62
0
0
0
% I
% Lys:
24
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
24
0
77
0
0
0
0
0
54
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
16
0
0
0
0
0
0
85
24
0
% N
% Pro:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
16
16
0
0
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
85
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
8
0
0
0
0
0
0
31
85
31
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _