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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D2
All Species:
17.27
Human Site:
T45
Identified Species:
29.23
UniProt:
Q9BX73
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX73
NP_001019551.1
214
22871
T45
A
T
A
E
P
E
L
T
S
A
G
A
A
Q
P
Chimpanzee
Pan troglodytes
XP_001136155
159
17650
Rhesus Macaque
Macaca mulatta
XP_001092363
214
22889
T45
A
T
A
E
P
E
L
T
S
A
G
A
A
H
P
Dog
Lupus familis
XP_539965
214
22907
T45
A
T
A
E
P
E
L
T
S
A
G
A
A
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0I4
213
22835
T45
A
T
A
E
L
D
L
T
P
S
G
A
A
H
L
Rat
Rattus norvegicus
Q566R2
213
22911
T45
A
T
A
E
L
D
L
T
P
S
G
A
A
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505963
240
26635
R52
G
R
D
S
P
R
V
R
P
Q
G
R
P
Q
D
Chicken
Gallus gallus
XP_424392
207
22136
N38
A
S
R
G
L
P
H
N
G
S
E
P
E
A
P
Frog
Xenopus laevis
Q5XGR4
198
21811
P37
N
T
S
P
V
T
Y
P
D
I
N
V
S
A
A
Zebra Danio
Brachydanio rerio
Q6DHN3
229
25358
T60
E
Q
P
E
E
N
V
T
E
S
G
S
V
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VY86
224
24341
P55
Q
L
G
S
G
M
G
P
S
S
S
S
S
S
A
Honey Bee
Apis mellifera
XP_391919
163
18251
Nematode Worm
Caenorhab. elegans
P61228
210
23832
L46
D
S
S
K
E
N
D
L
L
D
L
F
Y
V
S
Sea Urchin
Strong. purpuratus
XP_791119
200
22332
P38
E
N
D
R
I
I
V
P
E
H
E
E
C
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.7
99
96.2
N.A.
90.6
90.1
N.A.
63.7
73.3
67.2
67.2
N.A.
46.4
48.5
41.5
46.2
Protein Similarity:
100
71
99.5
96.7
N.A.
95.3
94.8
N.A.
69.5
83.1
76.1
74.2
N.A.
61.1
57.4
54.6
63.5
P-Site Identity:
100
0
93.3
93.3
N.A.
60
60
N.A.
20
13.3
6.6
26.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
0
93.3
93.3
N.A.
73.3
73.3
N.A.
26.6
26.6
20
46.6
N.A.
26.6
0
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
36
0
0
0
0
0
0
22
0
36
36
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
15
0
0
15
8
0
8
8
0
0
0
0
8
% D
% Glu:
15
0
0
43
15
22
0
0
15
0
15
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
8
8
0
8
0
8
0
50
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
29
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
22
0
36
8
8
0
8
0
0
0
15
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
15
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
8
29
8
0
22
22
0
0
8
8
0
36
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
0
0
0
15
0
% Q
% Arg:
0
8
8
8
0
8
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
15
15
15
0
0
0
0
29
36
8
15
15
8
8
% S
% Thr:
0
43
0
0
0
8
0
43
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
22
0
0
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _