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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D2
All Species:
15.76
Human Site:
Y63
Identified Species:
26.67
UniProt:
Q9BX73
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX73
NP_001019551.1
214
22871
Y63
G
G
A
A
S
W
E
Y
G
D
P
H
S
P
V
Chimpanzee
Pan troglodytes
XP_001136155
159
17650
I15
D
R
M
M
M
I
M
I
L
L
V
N
Y
R
P
Rhesus Macaque
Macaca mulatta
XP_001092363
214
22889
Y63
G
G
A
A
N
W
E
Y
G
D
P
H
S
P
V
Dog
Lupus familis
XP_539965
214
22907
Y63
A
G
A
Q
S
W
E
Y
G
D
P
H
S
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0I4
213
22835
S63
A
A
S
S
W
E
Y
S
D
P
N
S
P
V
I
Rat
Rattus norvegicus
Q566R2
213
22911
S63
A
A
S
S
W
E
Y
S
D
P
N
S
P
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505963
240
26635
Y70
D
R
P
Q
P
W
E
Y
T
D
P
R
S
P
L
Chicken
Gallus gallus
XP_424392
207
22136
Y56
P
A
A
A
T
W
A
Y
S
D
P
R
A
P
L
Frog
Xenopus laevis
Q5XGR4
198
21811
V55
R
D
P
L
G
P
L
V
L
C
S
Y
L
P
E
Zebra Danio
Brachydanio rerio
Q6DHN3
229
25358
E78
S
N
H
T
E
Q
Y
E
Y
N
P
P
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VY86
224
24341
A73
S
G
G
A
G
N
S
A
F
Y
P
L
G
P
N
Honey Bee
Apis mellifera
XP_391919
163
18251
V20
Y
R
P
E
G
P
L
V
M
C
K
F
L
P
K
Nematode Worm
Caenorhab. elegans
P61228
210
23832
R64
L
G
P
V
V
E
C
R
F
L
E
N
S
F
I
Sea Urchin
Strong. purpuratus
XP_791119
200
22332
E56
G
V
E
Y
N
P
V
E
P
L
V
K
C
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.7
99
96.2
N.A.
90.6
90.1
N.A.
63.7
73.3
67.2
67.2
N.A.
46.4
48.5
41.5
46.2
Protein Similarity:
100
71
99.5
96.7
N.A.
95.3
94.8
N.A.
69.5
83.1
76.1
74.2
N.A.
61.1
57.4
54.6
63.5
P-Site Identity:
100
0
93.3
86.6
N.A.
0
0
N.A.
46.6
46.6
6.6
26.6
N.A.
26.6
6.6
13.3
6.6
P-Site Similarity:
100
6.6
100
86.6
N.A.
20
20
N.A.
53.3
66.6
13.3
33.3
N.A.
26.6
6.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
22
29
29
0
0
8
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
15
0
0
8
0
0
% C
% Asp:
15
8
0
0
0
0
0
0
15
36
0
0
0
0
0
% D
% Glu:
0
0
8
8
8
22
29
15
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
8
0
8
8
% F
% Gly:
22
36
8
0
22
0
0
0
22
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
22
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
22
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% K
% Leu:
8
0
0
8
0
0
15
0
15
22
0
8
15
0
15
% L
% Met:
0
0
8
8
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
15
8
0
0
0
8
15
15
0
0
8
% N
% Pro:
8
0
29
0
8
22
0
0
8
15
50
8
15
65
8
% P
% Gln:
0
0
0
15
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
22
0
0
0
0
0
8
0
0
0
15
0
8
0
% R
% Ser:
15
0
15
15
15
0
8
15
8
0
8
15
43
8
0
% S
% Thr:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
8
8
0
8
15
0
0
15
0
0
15
29
% V
% Trp:
0
0
0
0
15
36
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
22
36
8
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _