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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D1
All Species:
20.91
Human Site:
S194
Identified Species:
57.5
UniProt:
Q9BX74
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX74
NP_114416.1
207
22327
S194
G
T
R
L
T
R
L
S
I
T
N
E
T
F
R
Chimpanzee
Pan troglodytes
XP_513448
207
22311
S194
G
T
R
L
T
R
L
S
I
T
N
E
T
F
R
Rhesus Macaque
Macaca mulatta
XP_001084483
207
22310
S194
G
T
R
L
T
R
L
S
I
T
N
E
T
Y
R
Dog
Lupus familis
XP_536690
208
22303
S195
G
T
R
L
T
R
L
S
I
T
N
E
T
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99MB3
208
22253
S195
G
T
R
L
T
R
L
S
I
T
N
E
T
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PLH4
197
22187
I185
A
R
L
T
R
L
S
I
T
N
E
T
Y
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2H1
178
19878
S166
A
G
I
H
I
V
R
S
D
N
T
T
Y
R
L
Honey Bee
Apis mellifera
XP_624839
186
20781
T173
G
A
G
I
H
I
V
T
S
N
N
F
T
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782102
195
21686
D183
K
L
I
K
M
G
V
D
N
E
T
Y
Y
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97
92.7
N.A.
85
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
N.A.
38.6
39.1
N.A.
40.1
Protein Similarity:
100
99.5
98
96.1
N.A.
89.9
N.A.
N.A.
N.A.
N.A.
N.A.
74.4
N.A.
54.5
56.5
N.A.
57.4
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
26.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
53.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
12
56
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
45
0
% F
% Gly:
67
12
12
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
12
12
12
0
12
56
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
12
56
0
12
56
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
34
67
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
56
0
12
56
12
0
0
0
0
0
0
23
78
% R
% Ser:
0
0
0
0
0
0
12
67
12
0
0
0
0
0
0
% S
% Thr:
0
56
0
12
56
0
0
12
12
56
23
23
67
0
0
% T
% Val:
0
0
0
0
0
12
23
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
34
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _