KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D1
All Species:
12.42
Human Site:
S45
Identified Species:
34.17
UniProt:
Q9BX74
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX74
NP_114416.1
207
22327
S45
T
S
A
G
G
E
E
S
L
K
C
E
D
L
K
Chimpanzee
Pan troglodytes
XP_513448
207
22311
S45
T
S
A
G
G
E
E
S
L
K
C
E
D
L
K
Rhesus Macaque
Macaca mulatta
XP_001084483
207
22310
L45
T
S
A
G
G
E
E
L
P
K
C
E
D
L
K
Dog
Lupus familis
XP_536690
208
22303
T46
A
A
A
G
G
E
E
T
L
K
C
E
D
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99MB3
208
22253
T46
G
A
V
G
G
E
E
T
P
K
C
E
D
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PLH4
197
22187
D36
H
S
L
G
N
D
V
D
S
C
D
K
L
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2H1
178
19878
H17
F
F
F
A
K
E
T
H
Q
I
N
V
D
C
N
Honey Bee
Apis mellifera
XP_624839
186
20781
V24
S
I
P
L
S
N
G
V
D
Y
T
Y
E
I
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782102
195
21686
E34
L
L
D
M
A
C
L
E
D
V
E
F
T
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97
92.7
N.A.
85
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
N.A.
38.6
39.1
N.A.
40.1
Protein Similarity:
100
99.5
98
96.1
N.A.
89.9
N.A.
N.A.
N.A.
N.A.
N.A.
74.4
N.A.
54.5
56.5
N.A.
57.4
P-Site Identity:
100
100
86.6
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
86.6
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
13.3
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
45
12
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
12
56
0
0
23
0
% C
% Asp:
0
0
12
0
0
12
0
12
23
0
12
0
67
0
12
% D
% Glu:
0
0
0
0
0
67
56
12
0
0
12
56
12
0
0
% E
% Phe:
12
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
12
0
0
67
56
0
12
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
12
0
0
0
12
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
56
0
12
0
0
45
% K
% Leu:
12
12
12
12
0
0
12
12
34
0
0
0
12
56
12
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
0
23
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
45
0
0
12
0
0
23
12
0
0
0
0
0
12
% S
% Thr:
34
0
0
0
0
0
12
23
0
0
12
0
12
0
0
% T
% Val:
0
0
12
0
0
0
12
12
0
12
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _