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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D1
All Species:
20.91
Human Site:
Y186
Identified Species:
57.5
UniProt:
Q9BX74
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX74
NP_114416.1
207
22327
Y186
S
S
Y
I
I
D
Y
Y
G
T
R
L
T
R
L
Chimpanzee
Pan troglodytes
XP_513448
207
22311
Y186
S
S
Y
I
I
D
Y
Y
G
T
R
L
T
R
L
Rhesus Macaque
Macaca mulatta
XP_001084483
207
22310
Y186
S
S
Y
I
I
D
Y
Y
G
T
R
L
T
R
L
Dog
Lupus familis
XP_536690
208
22303
Y187
S
S
Y
I
I
D
Y
Y
G
T
R
L
T
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MB3
208
22253
Y187
S
S
Y
I
I
D
Y
Y
G
T
R
L
T
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PLH4
197
22187
G177
D
Y
I
V
D
Y
Y
G
A
R
L
T
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2H1
178
19878
G158
A
Y
V
I
P
Y
Y
G
A
G
I
H
I
V
R
Honey Bee
Apis mellifera
XP_624839
186
20781
Y165
S
H
Y
V
M
P
Y
Y
G
A
G
I
H
I
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782102
195
21686
P175
Y
E
M
D
F
Y
A
P
K
L
I
K
M
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97
92.7
N.A.
85
N.A.
N.A.
N.A.
N.A.
N.A.
62.7
N.A.
38.6
39.1
N.A.
40.1
Protein Similarity:
100
99.5
98
96.1
N.A.
89.9
N.A.
N.A.
N.A.
N.A.
N.A.
74.4
N.A.
54.5
56.5
N.A.
57.4
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
60
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
23
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
12
12
56
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
23
67
12
12
0
0
12
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
12
12
0
0
% H
% Ile:
0
0
12
67
56
0
0
0
0
0
23
12
12
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
12
56
0
12
56
% L
% Met:
0
0
12
0
12
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
12
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
56
0
12
56
12
% R
% Ser:
67
56
0
0
0
0
0
0
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
56
0
12
56
0
0
% T
% Val:
0
0
12
23
0
0
0
0
0
0
0
0
0
12
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
23
67
0
0
34
89
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _