KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPM6
All Species:
7.27
Human Site:
S15
Identified Species:
20
UniProt:
Q9BX84
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BX84
NP_060132.3
2022
231708
S15
E
R
L
Q
S
Q
K
S
W
I
K
G
V
F
D
Chimpanzee
Pan troglodytes
XP_528327
2017
230942
V15
Q
K
S
W
I
K
G
V
F
D
K
R
E
C
S
Rhesus Macaque
Macaca mulatta
XP_001094459
2126
241799
S116
A
P
V
T
S
Q
K
S
W
I
K
G
V
F
D
Dog
Lupus familis
XP_541279
2031
232519
S17
I
D
Q
E
S
Q
K
S
W
I
E
G
V
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIR4
2028
232870
V11
K
K
S
W
I
E
G
V
F
Y
K
R
E
C
N
Rat
Rattus norvegicus
Q925B3
1862
212335
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425074
1869
212093
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025232
1774
201423
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8DYE2
2023
225520
D98
V
L
I
L
N
V
R
D
L
L
K
A
H
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
91.5
85.3
N.A.
78.1
52.5
N.A.
N.A.
53.2
N.A.
52
N.A.
31.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
93
90.8
N.A.
85.3
66.6
N.A.
N.A.
67.5
N.A.
65.7
N.A.
50.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
73.3
60
N.A.
6.6
0
N.A.
N.A.
0
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
80
80
N.A.
40
0
N.A.
N.A.
0
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% C
% Asp:
0
12
0
0
0
0
0
12
0
12
0
0
0
0
23
% D
% Glu:
12
0
0
12
0
12
0
0
0
0
12
0
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
23
0
0
0
0
34
0
% F
% Gly:
0
0
0
0
0
0
23
0
0
0
0
34
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
12
0
12
0
23
0
0
0
0
34
0
0
0
0
0
% I
% Lys:
12
23
0
0
0
12
34
0
0
0
56
0
0
0
0
% K
% Leu:
0
12
12
12
0
0
0
0
12
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
23
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
12
12
0
34
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
12
0
0
0
0
23
0
0
0
% R
% Ser:
0
0
23
0
34
0
0
34
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
0
12
0
0
12
0
23
0
0
0
0
34
0
0
% V
% Trp:
0
0
0
23
0
0
0
0
34
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _