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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP1 All Species: 20
Human Site: S112 Identified Species: 40
UniProt: Q9BX95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BX95 NP_110418.1 441 49108 S112 A G A L R R N S L T G E E G Q
Chimpanzee Pan troglodytes XP_522876 441 49079 S112 A G G L R R N S L T G E E G Q
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 A70 A N G L R R A A A P E A Y V Q
Dog Lupus familis XP_547850 445 49494 S116 V G A L R R N S L T D E E G E
Cat Felis silvestris
Mouse Mus musculus Q9JI99 430 47726 S101 A G S Q R R N S L T G E E G E
Rat Rattus norvegicus Q99P55 430 47631 S101 A G S L R R N S L T G E E G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426472 509 56506 L180 S A R R C G G L V T P A L A V
Frog Xenopus laevis NP_001091137 400 44326 A75 N G S Y A N G A P K Q G I A K
Zebra Danio Brachydanio rerio XP_001343219 437 48305 S108 V K P S R R N S L T G D A G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 N60 D K Q K Q S S N I Y N T N Y T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 A86 R R L G D P N A T V S A A P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47013 409 47353 Q62 L L V F T N N Q S F T L S R W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.8 89.8 N.A. 78.6 79.1 N.A. N.A. 55.9 37.8 57.5 N.A. N.A. 31.5 N.A. 32.8
Protein Similarity: 100 99.7 57.3 92.5 N.A. 84.8 86.6 N.A. N.A. 66.2 55 70 N.A. N.A. 51.4 N.A. 50.5
P-Site Identity: 100 93.3 33.3 80 N.A. 80 86.6 N.A. N.A. 6.6 6.6 60 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 93.3 40 86.6 N.A. 93.3 100 N.A. N.A. 20 26.6 66.6 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 42 9 17 0 9 0 9 25 9 0 0 25 17 17 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 0 9 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 42 42 0 25 % E
% Phe: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 50 17 9 0 9 17 0 0 0 42 9 0 50 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 17 0 9 0 0 0 0 0 9 0 0 0 0 9 % K
% Leu: 9 9 9 42 0 0 0 9 50 0 0 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 17 67 9 0 0 9 0 9 0 0 % N
% Pro: 0 0 9 0 0 9 0 0 9 9 9 0 0 9 0 % P
% Gln: 0 0 9 9 9 0 0 9 0 0 9 0 0 0 34 % Q
% Arg: 9 9 9 9 59 59 0 0 0 0 0 0 0 9 0 % R
% Ser: 9 0 25 9 0 9 9 50 9 0 9 0 9 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 59 9 9 0 0 9 % T
% Val: 17 0 9 0 0 0 0 0 9 9 0 0 0 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 9 0 0 0 0 0 9 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _