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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP1 All Species: 39.7
Human Site: S188 Identified Species: 79.39
UniProt: Q9BX95 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BX95 NP_110418.1 441 49108 S188 I R W P R P A S P P V V K L E
Chimpanzee Pan troglodytes XP_522876 441 49079 S188 I R W P R P A S P P V V K L E
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 S146 L K W P R P S S P P V V K L E
Dog Lupus familis XP_547850 445 49494 S192 I R W P R P A S P P V V K L E
Cat Felis silvestris
Mouse Mus musculus Q9JI99 430 47726 S177 I R W P R P A S P P V I K L E
Rat Rattus norvegicus Q99P55 430 47631 S177 I R W P R P A S P P V I K L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426472 509 56506 S256 I R W P R P A S P P V V K L E
Frog Xenopus laevis NP_001091137 400 44326 S151 L K W P R P S S P P V V K L E
Zebra Danio Brachydanio rerio XP_001343219 437 48305 S184 F R W P R P A S P P V V K V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 C133 I C W A R P A C P P A V R L Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 S162 I R W P R P L S P P V A P L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47013 409 47353 R143 P R A P P L H R I T L S E Y T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.8 89.8 N.A. 78.6 79.1 N.A. N.A. 55.9 37.8 57.5 N.A. N.A. 31.5 N.A. 32.8
Protein Similarity: 100 99.7 57.3 92.5 N.A. 84.8 86.6 N.A. N.A. 66.2 55 70 N.A. N.A. 51.4 N.A. 50.5
P-Site Identity: 100 100 80 100 N.A. 93.3 93.3 N.A. N.A. 100 80 86.6 N.A. N.A. 60 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. N.A. 73.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 67 0 0 0 9 9 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 84 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 67 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 0 0 75 0 0 % K
% Leu: 17 0 0 0 0 9 9 0 0 0 9 0 0 84 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 92 9 92 0 0 92 92 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 75 0 0 92 0 0 9 0 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 17 84 0 0 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 0 0 84 67 0 9 0 % V
% Trp: 0 0 92 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _