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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP1 All Species: 22.12
Human Site: T114 Identified Species: 44.24
UniProt: Q9BX95 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BX95 NP_110418.1 441 49108 T114 A L R R N S L T G E E G Q L A
Chimpanzee Pan troglodytes XP_522876 441 49079 T114 G L R R N S L T G E E G Q L A
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 P72 G L R R A A A P E A Y V Q K Y
Dog Lupus familis XP_547850 445 49494 T118 A L R R N S L T D E E G E L A
Cat Felis silvestris
Mouse Mus musculus Q9JI99 430 47726 T103 S Q R R N S L T G E E G E L V
Rat Rattus norvegicus Q99P55 430 47631 T103 S L R R N S L T G E E G E L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426472 509 56506 T182 R R C G G L V T P A L A V C R
Frog Xenopus laevis NP_001091137 400 44326 K77 S Y A N G A P K Q G I A K K Y
Zebra Danio Brachydanio rerio XP_001343219 437 48305 T110 P S R R N S L T G D A G Q E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 Y62 Q K Q S S N I Y N T N Y T I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 V88 L G D P N A T V S A A P V E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47013 409 47353 F64 V F T N N Q S F T L S R W Q K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.8 89.8 N.A. 78.6 79.1 N.A. N.A. 55.9 37.8 57.5 N.A. N.A. 31.5 N.A. 32.8
Protein Similarity: 100 99.7 57.3 92.5 N.A. 84.8 86.6 N.A. N.A. 66.2 55 70 N.A. N.A. 51.4 N.A. 50.5
P-Site Identity: 100 93.3 26.6 86.6 N.A. 73.3 86.6 N.A. N.A. 6.6 0 60 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 93.3 33.3 93.3 N.A. 86.6 100 N.A. N.A. 13.3 20 66.6 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 9 25 9 0 0 25 17 17 0 0 34 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 42 42 0 25 17 0 % E
% Phe: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 17 9 0 9 17 0 0 0 42 9 0 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 9 0 0 9 0 % I
% Lys: 0 9 0 0 0 0 0 9 0 0 0 0 9 17 9 % K
% Leu: 9 42 0 0 0 9 50 0 0 9 9 0 0 42 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 67 9 0 0 9 0 9 0 0 0 0 % N
% Pro: 9 0 0 9 0 0 9 9 9 0 0 9 0 0 0 % P
% Gln: 9 9 9 0 0 9 0 0 9 0 0 0 34 9 0 % Q
% Arg: 9 9 59 59 0 0 0 0 0 0 0 9 0 0 9 % R
% Ser: 25 9 0 9 9 50 9 0 9 0 9 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 9 59 9 9 0 0 9 0 9 % T
% Val: 9 0 0 0 0 0 9 9 0 0 0 9 17 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 9 0 0 0 0 0 9 0 0 9 9 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _