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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP1 All Species: 32.73
Human Site: T314 Identified Species: 65.45
UniProt: Q9BX95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BX95 NP_110418.1 441 49108 T314 F T L D T W S T S R G D T A E
Chimpanzee Pan troglodytes XP_522876 441 49079 T314 F T L D T W S T S R G D T A E
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 P272 P V S D Y Y S P T R A D T T T
Dog Lupus familis XP_547850 445 49494 T318 F T L D T W S T S R G D T A E
Cat Felis silvestris
Mouse Mus musculus Q9JI99 430 47726 T303 F T L D T W S T S R G D T A E
Rat Rattus norvegicus Q99P55 430 47631 T303 F T L D T W S T S R G D T A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426472 509 56506 T382 F T L D T W S T S R G D T A Q
Frog Xenopus laevis NP_001091137 400 44326 T277 P K M N H Y S T T R A D T T T
Zebra Danio Brachydanio rerio XP_001343219 437 48305 T310 F T L D T W S T S R G D T A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 P259 P C S K K W T P T R G D T T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 S288 P T Q D G W S S T R A D T I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47013 409 47353 P270 V K P V D E C P C F Q D S V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.8 89.8 N.A. 78.6 79.1 N.A. N.A. 55.9 37.8 57.5 N.A. N.A. 31.5 N.A. 32.8
Protein Similarity: 100 99.7 57.3 92.5 N.A. 84.8 86.6 N.A. N.A. 66.2 55 70 N.A. N.A. 51.4 N.A. 50.5
P-Site Identity: 100 100 33.3 100 N.A. 100 100 N.A. N.A. 93.3 33.3 93.3 N.A. N.A. 33.3 N.A. 46.6
P-Site Similarity: 100 100 46.6 100 N.A. 100 100 N.A. N.A. 100 60 100 N.A. N.A. 46.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 25 0 0 59 9 % A
% Cys: 0 9 0 0 0 0 9 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 75 9 0 0 0 0 0 0 100 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 42 % E
% Phe: 59 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 67 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 17 0 9 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 34 0 9 0 0 0 0 25 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 17 % Q
% Arg: 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 % R
% Ser: 0 0 17 0 0 0 84 9 59 0 0 0 9 0 0 % S
% Thr: 0 67 0 0 59 0 9 67 34 0 0 0 92 25 17 % T
% Val: 9 9 0 9 0 0 0 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 17 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _