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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGPP1 All Species: 26.36
Human Site: Y290 Identified Species: 52.73
UniProt: Q9BX95 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BX95 NP_110418.1 441 49108 Y290 N F N Q T H K Y A P F I I I G
Chimpanzee Pan troglodytes XP_522876 441 49079 Y290 N F N Q T H K Y A P F I I I G
Rhesus Macaque Macaca mulatta XP_001107876 399 44723 L248 R L D S A S P L F P V C V I V
Dog Lupus familis XP_547850 445 49494 Y294 N F N Q T H K Y A P L I I I G
Cat Felis silvestris
Mouse Mus musculus Q9JI99 430 47726 Y279 N F N Q T Y K Y A P L I I I G
Rat Rattus norvegicus Q99P55 430 47631 Y279 N F N Q T Y K Y A P L I I I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426472 509 56506 Y358 D F N L T Y K Y A P L I I I S
Frog Xenopus laevis NP_001091137 400 44326 L253 K V I I G H P L S P V F T I I
Zebra Danio Brachydanio rerio XP_001343219 437 48305 Y286 T F N R T H P Y A P L M I I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122506 399 45587 W235 Y Y V L T N I W A L A I L I A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787135 411 46436 Y264 T F L I T H P Y A P L F S M A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47013 409 47353 W245 G L R I E E H W W F P L F S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 37.8 89.8 N.A. 78.6 79.1 N.A. N.A. 55.9 37.8 57.5 N.A. N.A. 31.5 N.A. 32.8
Protein Similarity: 100 99.7 57.3 92.5 N.A. 84.8 86.6 N.A. N.A. 66.2 55 70 N.A. N.A. 51.4 N.A. 50.5
P-Site Identity: 100 100 13.3 93.3 N.A. 86.6 86.6 N.A. N.A. 66.6 20 60 N.A. N.A. 26.6 N.A. 40
P-Site Similarity: 100 100 26.6 93.3 N.A. 93.3 93.3 N.A. N.A. 80 26.6 73.3 N.A. N.A. 53.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 75 0 9 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 67 0 0 0 0 0 0 9 9 17 17 9 0 0 % F
% Gly: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 42 % G
% His: 0 0 0 0 0 50 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 25 0 0 9 0 0 0 0 59 59 84 9 % I
% Lys: 9 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 9 17 0 0 0 17 0 9 50 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % M
% Asn: 42 0 59 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 34 0 0 84 9 0 0 0 0 % P
% Gln: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 9 0 0 9 0 0 0 9 9 17 % S
% Thr: 17 0 0 0 75 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 9 9 0 0 0 0 0 0 0 17 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 17 9 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 25 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _