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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGR4 All Species: 21.21
Human Site: S878 Identified Species: 46.67
UniProt: Q9BXB1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXB1 NP_060960.2 951 104475 S878 S C K H L I K S H S C P A L A
Chimpanzee Pan troglodytes XP_001168558 350 38942 N278 P V L Y V F F N P K F K E D W
Rhesus Macaque Macaca mulatta XP_001090038 1085 118005 S1012 S C K H L I K S H S C P A L A
Dog Lupus familis XP_534098 1088 121134 S1015 S C K H L I K S H S C P A L A
Cat Felis silvestris
Mouse Mus musculus A2ARI4 951 104131 S878 S C K H L I K S H S C P V L T
Rat Rattus norvegicus Q9Z2H4 951 104120 S878 S C K H L I K S H S C P V L T
Wallaby Macropus eugenll Q6YNB6 694 78462 A622 F Y P I N S C A N P F L Y A V
Platypus Ornith. anatinus XP_001517774 835 92770 H763 C K H L I K S H S C P A L A V
Chicken Gallus gallus P79763 693 78680 A621 F Y P I N S C A N P F L Y A I
Frog Xenopus laevis NP_001089881 955 105573 S882 P C K H L I K S H S C P T L A
Zebra Danio Brachydanio rerio XP_687184 961 103852 S888 R H L V K S H S C P A L M G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.7 86.7 79.1 N.A. 92.9 93 21.9 76.9 22.7 74.9 60 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.7 87.2 82.5 N.A. 95.5 95.5 40.9 82.1 40.4 83.9 74.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 86.6 86.6 0 0 0 86.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 86.6 86.6 13.3 6.6 13.3 86.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 19 0 0 10 10 28 28 37 % A
% Cys: 10 55 0 0 0 0 19 0 10 10 55 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 19 0 0 0 0 10 10 0 0 0 28 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 10 10 55 0 0 10 10 55 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 10 55 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 10 55 0 10 10 55 0 0 10 0 10 0 0 0 % K
% Leu: 0 0 19 10 55 0 0 0 0 0 0 28 10 55 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 19 0 0 10 19 0 0 0 0 0 10 % N
% Pro: 19 0 19 0 0 0 0 0 10 28 10 55 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 46 0 0 0 0 28 10 64 10 55 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 19 % T
% Val: 0 10 0 10 10 0 0 0 0 0 0 0 19 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 19 0 10 0 0 0 0 0 0 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _