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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPL
All Species:
10
Human Site:
S295
Identified Species:
22
UniProt:
Q9BXD5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXD5
NP_110396.1
320
35163
S295
A
S
R
E
F
T
D
S
A
E
A
K
L
K
S
Chimpanzee
Pan troglodytes
XP_514043
320
35172
S295
A
S
R
E
F
T
D
S
A
E
A
K
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001114494
320
35156
S295
A
S
R
E
F
T
D
S
A
E
A
K
L
K
S
Dog
Lupus familis
XP_547433
507
55538
N482
A
S
R
E
F
I
D
N
A
K
A
K
L
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCJ9
320
35112
K295
A
T
Q
E
F
T
A
K
A
E
A
K
L
K
S
Rat
Rattus norvegicus
Q66H59
320
35097
N295
A
T
Q
E
F
T
A
N
A
E
A
K
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515973
309
33856
R282
G
I
P
M
G
P
P
R
L
P
L
Q
S
A
S
Chicken
Gallus gallus
Q5ZKD4
308
33628
R281
G
I
P
M
G
P
P
R
L
P
L
V
G
A
S
Frog
Xenopus laevis
Q3B8E8
305
33707
S279
S
G
I
P
L
G
P
S
R
L
P
L
Y
S
S
Zebra Danio
Brachydanio rerio
Q6NYR8
307
33203
L283
L
P
M
G
P
P
R
L
P
L
L
P
C
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791444
316
34827
L291
M
G
P
A
R
S
P
L
H
N
P
S
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
58.7
N.A.
85.6
88.4
N.A.
80.9
68.1
52.8
53.1
N.A.
N.A.
N.A.
N.A.
41.2
Protein Similarity:
100
99.6
99
61.3
N.A.
92.8
94.6
N.A.
88.1
80.3
70.6
68.7
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
6.6
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
13.3
6.6
20
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
0
0
10
0
0
19
0
55
0
55
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
37
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
55
0
0
0
0
0
46
0
0
0
10
10
% E
% Phe:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
19
0
10
19
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
19
10
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
55
0
55
0
% K
% Leu:
10
0
0
0
10
0
0
19
19
19
28
10
55
0
0
% L
% Met:
10
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% N
% Pro:
0
10
28
10
10
28
37
0
10
19
19
10
10
10
0
% P
% Gln:
0
0
19
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
37
0
10
0
10
19
10
0
0
0
0
0
0
% R
% Ser:
10
37
0
0
0
10
0
37
0
0
0
10
10
10
82
% S
% Thr:
0
19
0
0
0
46
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _