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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPZ1 All Species: 12.94
Human Site: S425 Identified Species: 47.44
UniProt: Q9BXG8 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXG8 NP_115956.3 430 49445 S425 A L R G K M R S A S S L R _ _
Chimpanzee Pan troglodytes XP_001136809 408 46916
Rhesus Macaque Macaca mulatta XP_001109987 382 44018 S377 A L R G K M R S A S S L R _ _
Dog Lupus familis XP_546045 367 42244 S362 R G T P V E K S S S S L T _ _
Cat Felis silvestris
Mouse Mus musculus Q99MY0 378 43073 T373 S L V G K R R T V S S F R _ _
Rat Rattus norvegicus Q6AXY9 400 45796 T395 S L V G K R R T I S S F R _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084776 670 80035 A615 D L N D Q L Q A Q L T A T K K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 83.4 56.7 N.A. 43.9 43.9 N.A. N.A. N.A. 20.8 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93 86.2 67.6 N.A. 59.7 59.5 N.A. N.A. N.A. 37.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 30.7 N.A. 53.8 53.8 N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 46.1 N.A. 69.2 69.2 N.A. N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 0 0 0 0 15 29 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % F
% Gly: 0 15 0 58 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 58 0 15 0 0 0 0 0 0 15 15 % K
% Leu: 0 72 0 0 0 15 0 0 0 15 0 43 0 0 0 % L
% Met: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 15 0 15 0 15 0 0 0 0 0 0 % Q
% Arg: 15 0 29 0 0 29 58 0 0 0 0 0 58 0 0 % R
% Ser: 29 0 0 0 0 0 0 43 15 72 72 0 0 0 0 % S
% Thr: 0 0 15 0 0 0 0 29 0 0 15 0 29 0 0 % T
% Val: 0 0 29 0 15 0 0 0 15 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 72 72 % _