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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A2 All Species: 30.3
Human Site: S241 Identified Species: 44.44
UniProt: Q9BXI2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXI2 NP_114153.1 301 32580 S241 K S R I Q V L S M Y G K Q A G
Chimpanzee Pan troglodytes XP_527046 301 32548 S241 K S R I Q V L S M Y G K Q A G
Rhesus Macaque Macaca mulatta XP_001092357 301 32627 S241 K S R I Q V L S M Y G K Q A G
Dog Lupus familis XP_544307 301 32634 S241 K S R I Q V L S I S G K Q A G
Cat Felis silvestris
Mouse Mus musculus Q9WVD5 301 32805 S241 K S R I Q V L S M T G K Q T G
Rat Rattus norvegicus P97521 301 33135 P241 K S R F Q T A P P G K Y P N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513116 301 32654 S241 K S R I Q V L S M S G K Q A G
Chicken Gallus gallus NP_001008442 301 32763 S241 K S R I Q V L S M A G K Q T G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4QNX2 288 31518 L229 M D V I K S R L Q V D G V S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQG4 306 32934 P246 K S R L Q S A P E G T Y K H G
Honey Bee Apis mellifera XP_624973 314 34822 Q254 D V V K S R I Q V K N L K T P
Nematode Worm Caenorhab. elegans Q27257 312 33116 P237 K S R L Q T A P E G K Y P D G
Sea Urchin Strong. purpuratus XP_788407 332 36308 S268 K S R I Q V Q S L V G K M P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 L241 T D V V K S V L Q V D D Y K N
Baker's Yeast Sacchar. cerevisiae Q12289 327 34736 T262 L A V F P I D T I K T K L Q A
Red Bread Mold Neurospora crassa Q01356 363 39383 P294 K S R M Q T S P I G G G G D N
Conservation
Percent
Protein Identity: 100 99.6 98.3 87 N.A. 85 33.5 N.A. 81.4 75.7 N.A. 30.5 N.A. 30.7 47.7 31.4 44.2
Protein Similarity: 100 99.6 98.6 92.6 N.A. 90.6 50.5 N.A. 88.3 88.6 N.A. 48.5 N.A. 47.7 64.3 48 63.2
P-Site Identity: 100 100 100 86.6 N.A. 86.6 33.3 N.A. 93.3 86.6 N.A. 13.3 N.A. 33.3 0 33.3 66.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 33.3 N.A. 93.3 86.6 N.A. 26.6 N.A. 46.6 20 40 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 21.1 27.5
Protein Similarity: N.A. N.A. N.A. 50.8 39.4 41.8
P-Site Identity: N.A. N.A. N.A. 0 6.6 33.3
P-Site Similarity: N.A. N.A. N.A. 20 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 19 0 0 7 0 0 0 32 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 13 0 0 0 0 7 0 0 0 13 7 0 13 0 % D
% Glu: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 25 57 13 7 0 75 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 57 0 7 7 0 19 0 0 0 0 0 0 % I
% Lys: 75 0 0 7 13 0 0 0 0 13 13 57 13 7 0 % K
% Leu: 7 0 0 13 0 0 44 13 7 0 0 7 7 0 0 % L
% Met: 7 0 0 7 0 0 0 0 38 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 13 % N
% Pro: 0 0 0 0 7 0 0 25 7 0 0 0 13 7 7 % P
% Gln: 0 0 0 0 75 0 7 7 13 0 0 0 44 7 0 % Q
% Arg: 0 0 75 0 0 7 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 75 0 0 7 19 7 50 0 13 0 0 0 7 0 % S
% Thr: 7 0 0 0 0 19 0 7 0 7 13 0 0 19 0 % T
% Val: 0 7 25 7 0 50 7 0 7 19 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 19 0 19 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _