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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D10A
All Species:
14.55
Human Site:
T499
Identified Species:
35.56
UniProt:
Q9BXI6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXI6
NP_114143.1
508
57118
T499
H
R
S
Q
E
S
L
T
S
Q
E
S
E
D
T
Chimpanzee
Pan troglodytes
XP_001139751
515
57891
T506
H
R
S
Q
E
S
L
T
S
Q
E
S
E
D
T
Rhesus Macaque
Macaca mulatta
XP_001108536
508
56949
T499
H
C
S
Q
E
S
L
T
S
Q
E
S
E
D
T
Dog
Lupus familis
XP_543476
555
61272
H538
H
R
S
Q
D
S
V
H
H
C
S
Q
E
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P58802
500
56184
T491
H
H
S
Q
E
S
L
T
S
Q
E
S
E
D
T
Rat
Rattus norvegicus
Q6P6R7
749
85170
H646
N
V
T
H
D
A
A
H
A
Q
M
D
V
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415301
474
53889
C465
H
Q
S
K
E
S
L
C
S
R
E
S
E
D
T
Frog
Xenopus laevis
Q6GLZ0
342
39660
R334
D
K
L
R
E
K
Q
R
L
Q
L
A
S
E
E
Zebra Danio
Brachydanio rerio
Q6PBU5
356
41604
R348
S
K
L
R
E
S
C
R
A
R
I
I
A
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623824
357
41572
S349
R
K
T
T
E
Q
T
S
F
S
T
V
N
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
98.2
83.7
N.A.
90.7
24
N.A.
N.A.
75.1
24.7
25
N.A.
N.A.
37.9
N.A.
N.A.
Protein Similarity:
100
98.6
98.4
85.9
N.A.
93.3
35.7
N.A.
N.A.
81.6
38.3
39.5
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
40
N.A.
93.3
6.6
N.A.
N.A.
73.3
13.3
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
53.3
N.A.
93.3
40
N.A.
N.A.
93.3
40
46.6
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
20
0
0
10
10
0
0
% A
% Cys:
0
10
0
0
0
0
10
10
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
20
0
0
0
0
0
0
10
0
60
0
% D
% Glu:
0
0
0
0
80
0
0
0
0
0
50
0
60
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
60
10
0
10
0
0
0
20
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
30
0
10
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
20
0
0
0
50
0
10
0
10
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
50
0
10
10
0
0
60
0
10
0
0
0
% Q
% Arg:
10
30
0
20
0
0
0
20
0
20
0
0
0
10
0
% R
% Ser:
10
0
60
0
0
70
0
10
50
10
10
50
10
10
0
% S
% Thr:
0
0
20
10
0
0
10
40
0
0
10
0
0
0
60
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _