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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM120A All Species: 27.27
Human Site: S122 Identified Species: 60
UniProt: Q9BXJ8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXJ8 NP_114131.1 343 40610 S122 N V N V T L L S K Q A K F A Y
Chimpanzee Pan troglodytes XP_528665 418 47889 V197 K G H T P G R V C H G R F A Y
Rhesus Macaque Macaca mulatta XP_001109513 343 40701 S122 N V N V T L L S K Q A K F A Y
Dog Lupus familis XP_536847 414 48217 S193 N V N V T L L S K Q A K F A Y
Cat Felis silvestris
Mouse Mus musculus Q8C1E7 343 40733 S122 N V N V T L L S K Q A K F A Y
Rat Rattus norvegicus Q5HZE2 343 40639 S122 N V N V T L L S K Q A K F A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415767 338 40403 S117 N V N V T L L S K Q A K F A Y
Frog Xenopus laevis A1L2R7 336 40306 S121 N V N V T L L S K Q A K F A Y
Zebra Danio Brachydanio rerio A3KNK1 341 40666 N121 N V N V T L L N K Q S K F A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U1M2 387 45468 L115 G D V N V S I L N R N D K V R
Honey Bee Apis mellifera XP_624968 353 41571 L111 G N V N V S I L N K S D K F K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.3 98.5 77.2 N.A. 94.7 93.8 N.A. N.A. 78.1 76.3 70.2 N.A. 42.6 49 N.A. N.A.
Protein Similarity: 100 64.8 98.8 79.4 N.A. 97.6 97.6 N.A. N.A. 88.6 87.7 84.8 N.A. 59.1 66.2 N.A. N.A.
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 13.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 64 0 0 82 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 19 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 82 10 0 % F
% Gly: 19 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 73 10 0 73 19 0 10 % K
% Leu: 0 0 0 0 0 73 73 19 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 73 10 73 19 0 0 0 10 19 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 10 0 10 0 0 10 % R
% Ser: 0 0 0 0 0 19 0 64 0 0 19 0 0 0 0 % S
% Thr: 0 0 0 10 73 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 73 19 73 19 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _