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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM120A
All Species:
18.79
Human Site:
S335
Identified Species:
41.33
UniProt:
Q9BXJ8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXJ8
NP_114131.1
343
40610
S335
V
V
H
H
K
F
H
S
Q
R
H
G
S
K
K
Chimpanzee
Pan troglodytes
XP_528665
418
47889
K410
V
V
H
A
K
L
Q
K
N
R
G
K
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001109513
343
40701
S335
V
V
H
Q
K
F
H
S
Q
W
H
G
S
K
K
Dog
Lupus familis
XP_536847
414
48217
S406
V
V
H
Q
K
F
H
S
Q
R
H
G
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1E7
343
40733
S335
V
V
H
Q
K
F
H
S
Q
Q
H
G
N
K
K
Rat
Rattus norvegicus
Q5HZE2
343
40639
S335
V
V
H
Q
K
F
H
S
Q
Q
H
G
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415767
338
40403
N330
V
V
H
Q
K
F
Q
N
Q
S
K
D
T
K
R
Frog
Xenopus laevis
A1L2R7
336
40306
T324
F
L
G
N
F
F
T
T
L
R
V
V
H
Q
K
Zebra Danio
Brachydanio rerio
A3KNK1
341
40666
D334
V
V
Y
H
K
Y
M
D
Q
D
K
A
K
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1M2
387
45468
E328
V
V
P
E
K
I
R
E
R
A
K
E
R
Y
R
Honey Bee
Apis mellifera
XP_624968
353
41571
E323
V
I
R
Q
K
L
R
E
R
V
K
Y
H
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.3
98.5
77.2
N.A.
94.7
93.8
N.A.
N.A.
78.1
76.3
70.2
N.A.
42.6
49
N.A.
N.A.
Protein Similarity:
100
64.8
98.8
79.4
N.A.
97.6
97.6
N.A.
N.A.
88.6
87.7
84.8
N.A.
59.1
66.2
N.A.
N.A.
P-Site Identity:
100
40
86.6
93.3
N.A.
80
86.6
N.A.
N.A.
46.6
20
33.3
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
53.3
86.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
46.6
46.6
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
19
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
0
10
64
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
46
0
10
0
% G
% His:
0
0
64
19
0
0
46
0
0
0
46
0
19
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
91
0
0
10
0
0
37
10
10
64
55
% K
% Leu:
0
10
0
0
0
19
0
0
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
10
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
55
0
0
19
0
64
19
0
0
0
10
10
% Q
% Arg:
0
0
10
0
0
0
19
0
19
37
0
0
10
0
19
% R
% Ser:
0
0
0
0
0
0
0
46
0
10
0
0
37
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
0
0
19
0
0
% T
% Val:
91
82
0
0
0
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _