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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEMGN
All Species:
9.39
Human Site:
Y449
Identified Species:
34.44
UniProt:
Q9BXL5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXL5
NP_060907.2
484
55341
Y449
Q
E
D
A
K
D
A
Y
T
F
P
Q
E
M
K
Chimpanzee
Pan troglodytes
XP_001156269
484
55387
Y449
Q
E
D
A
K
D
V
Y
T
F
P
Q
E
M
K
Rhesus Macaque
Macaca mulatta
XP_001113778
484
55354
Y449
Q
E
D
A
K
D
V
Y
T
F
P
Q
E
T
K
Dog
Lupus familis
XP_532005
476
54012
K448
R
E
M
R
E
K
P
K
A
E
E
P
E
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERZ0
503
55024
G460
A
Q
D
S
E
N
A
G
A
F
S
Q
D
F
T
Rat
Rattus norvegicus
Q6AZ54
514
56554
G474
A
Q
D
I
E
D
A
G
A
F
S
Q
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_705649
198
22242
S171
Y
N
D
V
P
E
Q
S
S
I
A
I
P
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
91.7
65.2
N.A.
39.3
42.7
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
94.4
75.8
N.A.
51.8
56
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
13.3
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
33.3
N.A.
60
66.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
43
0
0
43
0
43
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
86
0
0
58
0
0
0
0
0
0
29
0
0
% D
% Glu:
0
58
0
0
43
15
0
0
0
15
15
0
58
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
72
0
0
0
15
15
% F
% Gly:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
15
0
15
0
15
0
% I
% Lys:
0
0
0
0
43
15
0
15
0
0
0
0
0
0
43
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
0
43
0
% M
% Asn:
0
15
0
0
0
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
15
0
0
0
43
15
15
0
15
% P
% Gln:
43
29
0
0
0
0
15
0
0
0
0
72
0
0
0
% Q
% Arg:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
0
0
15
15
0
29
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
43
0
0
0
0
15
15
% T
% Val:
0
0
0
15
0
0
29
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _